High Prescribing and State-Level Variation in Z-Drug Use Among Medicare Patients
Discussion Contrary to the Beers criteria, Z-drugs are prescribed to older adults at high rates. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - June 7, 2023 Category: Psychiatry Authors: Anderson, Kaitlin E. Gifeisman, Rachel I. Basting, James L. Harris, Donovan J. Rajan, Antonica R. McCall, Kenneth L. Piper, Brian J. Tags: Original Paper Source Type: research

Maternal exposure to zolpidem and risk of specific birth defects
J Sleep Res. 2023 Jun 2:e13958. doi: 10.1111/jsr.13958. Online ahead of print.ABSTRACTZolpidem is a non-benzodiazepine agent indicated for treatment of insomnia. While zolpidem crosses the placenta, little is known about its safety in pregnancy. We assessed associations between self-reported zolpidem use 1 month before pregnancy through to the end of the third month ("early pregnancy") and specific birth defects using data from two multi-site case-control studies: National Birth Defects Prevention Study and Slone Epidemiology Center Birth Defects Study. Analysis included 39,711 birth defect cases and 23,035 controls withou...
Source: Journal of Sleep Research - June 3, 2023 Category: Sleep Medicine Authors: Meredith M Howley Martha M Werler Sarah C Fisher Melissa Tracy Alissa R Van Zutphen Eleni A Papadopoulos Craig Hansen Elizabeth C Ailes Jennita Reefhuis Mollie E Wood Marilyn L Browne National Birth Defects Prevention Study Source Type: research

Maternal exposure to zolpidem and risk of specific birth defects
J Sleep Res. 2023 Jun 2:e13958. doi: 10.1111/jsr.13958. Online ahead of print.ABSTRACTZolpidem is a non-benzodiazepine agent indicated for treatment of insomnia. While zolpidem crosses the placenta, little is known about its safety in pregnancy. We assessed associations between self-reported zolpidem use 1 month before pregnancy through to the end of the third month ("early pregnancy") and specific birth defects using data from two multi-site case-control studies: National Birth Defects Prevention Study and Slone Epidemiology Center Birth Defects Study. Analysis included 39,711 birth defect cases and 23,035 controls withou...
Source: Journal of Sleep Research - June 3, 2023 Category: Sleep Medicine Authors: Meredith M Howley Martha M Werler Sarah C Fisher Melissa Tracy Alissa R Van Zutphen Eleni A Papadopoulos Craig Hansen Elizabeth C Ailes Jennita Reefhuis Mollie E Wood Marilyn L Browne National Birth Defects Prevention Study Source Type: research

Maternal exposure to zolpidem and risk of specific birth defects
J Sleep Res. 2023 Jun 2:e13958. doi: 10.1111/jsr.13958. Online ahead of print.ABSTRACTZolpidem is a non-benzodiazepine agent indicated for treatment of insomnia. While zolpidem crosses the placenta, little is known about its safety in pregnancy. We assessed associations between self-reported zolpidem use 1 month before pregnancy through to the end of the third month ("early pregnancy") and specific birth defects using data from two multi-site case-control studies: National Birth Defects Prevention Study and Slone Epidemiology Center Birth Defects Study. Analysis included 39,711 birth defect cases and 23,035 controls withou...
Source: Journal of Sleep Research - June 3, 2023 Category: Sleep Medicine Authors: Meredith M Howley Martha M Werler Sarah C Fisher Melissa Tracy Alissa R Van Zutphen Eleni A Papadopoulos Craig Hansen Elizabeth C Ailes Jennita Reefhuis Mollie E Wood Marilyn L Browne National Birth Defects Prevention Study Source Type: research

Pharmacological and non-pharmacological treatment options for sleep disturbances in Alzheimer's disease
Expert Rev Neurother. 2023 Jun 2:1-14. doi: 10.1080/14737175.2023.2214316. Online ahead of print.ABSTRACTINTRODUCTION: Alzheimer's disease (AD) is one of the most common neurodegenerative disorders among the older population. Sleep disruption and circadian rhythm disorders often develop in AD patients, and many experience sleeping difficulties requiring pharmacological and non-pharmacological interventions.AREAS COVERED: This review appraised the evidence from clinical studies on various pharmacological and non-pharmacological therapies for sleep disturbances in AD patients and proposed an algorithm to manage sleep disturb...
Source: Expert Review of Neurotherapeutics - June 2, 2023 Category: Neurology Authors: Binish Javed Amaan Javed Chia Siang Kow Syed Shahzad Hasan Source Type: research