Racial disparities in hair loss episodes in patients with alopecia areata: A retrospective cohort study
Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss. Although most AA patients experience hair loss that resolves spontaneously, some may experience episodic disease flares which increase the cumulative disease burden and impairment of quality of life (QoL). (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - May 9, 2024 Category: Dermatology Authors: Li-Chi Chen, Navya Baranwal, Rachel K. Lim, Helen Zhang, Abrar A. Qureshi, Eunyoung Cho Tags: Letters to the Editor Source Type: research
Infectious events in patients with alopecia areata treated with JAK inhibitors: low burden and minimal impact on persistence in treatment
CONCLUSION: It can be stated that, during treatment with JAKi in AA patients, infectious events may occur, but in most cases these events are easily manageable and do not result in permanent discontinuation of the drug.PMID:38717372 | DOI:10.1080/14740338.2024.2348571 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - May 8, 2024 Category: Drugs & Pharmacology Authors: Giacomo Caldarola Lorenzo Maria Pinto Francesco Bellinato Nicoletta Bernardini Elena Campione Andrea Chiricozzi Laura Colonna Clara De Simone Laura Diluvio Paolo Gisondi Enrico Matteini Eleonora Tomassetti Ersilia Tolino Luca Bianchi Ketty Peris Source Type: research
Air pollution and skin diseases: A comprehensive evaluation of the associated mechanism
Ecotoxicol Environ Saf. 2024 May 7;278:116429. doi: 10.1016/j.ecoenv.2024.116429. Online ahead of print.ABSTRACTAir pollutants deteriorate the survival environment and endanger human health around the world. A large number of studies have confirmed that air pollution jeopardizes multiple organs, such as the cardiovascular, respiratory, and central nervous systems. Skin is the largest organ and the first barrier that protects us from the outside world. Air pollutants such as particulate matter (PM), polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds (VOCs) will affect the structure and function of the skin ...
Source: Ecotoxicology and Environmental Safety - May 8, 2024 Category: Environmental Health Authors: Xiaoyu Gu Zhengrui Li Juan Su Source Type: research
The clinical and immunological features of alopecia areata following SARS-CoV-2 infection or COVID-19 vaccines
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - May 8, 2024 Category: Drugs & Pharmacology Authors: Shiqi FuXiuzu Songa The Fourth Clinical Medical College, Zhejiang Chinese Medical University, Zhejiang, Chinab Department of Dermatology, Hangzhou Third People ’s Hospital, Affiliated Hangzhou Dermatology Hospital, Hangzhou, China Source Type: research
Insights into systemic lupus erythematosus: a retrospective observational study of clinical features, autoantibodies, and gender-related differences
This study aims to analyze the clinical and immunologic features of SLE in Jordan, while also investigating the impact of age and gender on disease presentation. The study included 275 patients diagnosed with SLE. Data were collected through meticulous patient interviews and thorough examination of patient hospital records. The cohort exhibited a mean age of 36.8 ± 12.9 years, with an average disease duration of 7.0 ± 7.8 years. The mean age at diagnosis was 29.9 ± 12.1 years, and the female to male ratio was 7.8:1. The most frequently observed symptoms were arthralgia (90.2%), fatigue (80.7%), hematolog...
Source: Rheumatology International - May 8, 2024 Category: Rheumatology Source Type: research
Evaluation of CoVid-19 infection among vaccinated and unvaccinated individuals using biochemical markers
Bioinformation. 2024 Mar 31;20(3):223-228. doi: 10.6026/973206300200223. eCollection 2024.ABSTRACTThe evaluation of infection rate for CoVid-19 cases among vaccinated and unvaccinated individuals using haematological parameters is of interest. Data such as age, gender, occupation, location, signs and symptoms, length of symptoms, date of sample collection and report generation, status of vaccinations, and outcome available in the database was used in this analysis. Ferritin levels, D-dimer values, CRP, troponin-1 levels and platelet count of each CoVid-19 patient were recorded and analysed. Data shows that maximum number o...
Source: Bioinformation - May 7, 2024 Category: Bioinformatics Authors: Allavarapu Ramya Sree K Sethumadhavan S P Tejaswi Pullakanam Purimitla Usharani Source Type: research
Evaluation of CoVid-19 infection among vaccinated and unvaccinated individuals using biochemical markers
Bioinformation. 2024 Mar 31;20(3):223-228. doi: 10.6026/973206300200223. eCollection 2024.ABSTRACTThe evaluation of infection rate for CoVid-19 cases among vaccinated and unvaccinated individuals using haematological parameters is of interest. Data such as age, gender, occupation, location, signs and symptoms, length of symptoms, date of sample collection and report generation, status of vaccinations, and outcome available in the database was used in this analysis. Ferritin levels, D-dimer values, CRP, troponin-1 levels and platelet count of each CoVid-19 patient were recorded and analysed. Data shows that maximum number o...
Source: Bioinformation - May 7, 2024 Category: Bioinformatics Authors: Allavarapu Ramya Sree K Sethumadhavan S P Tejaswi Pullakanam Purimitla Usharani Source Type: research
Evaluation of CoVid-19 infection among vaccinated and unvaccinated individuals using biochemical markers
Bioinformation. 2024 Mar 31;20(3):223-228. doi: 10.6026/973206300200223. eCollection 2024.ABSTRACTThe evaluation of infection rate for CoVid-19 cases among vaccinated and unvaccinated individuals using haematological parameters is of interest. Data such as age, gender, occupation, location, signs and symptoms, length of symptoms, date of sample collection and report generation, status of vaccinations, and outcome available in the database was used in this analysis. Ferritin levels, D-dimer values, CRP, troponin-1 levels and platelet count of each CoVid-19 patient were recorded and analysed. Data shows that maximum number o...
Source: Bioinformation - May 7, 2024 Category: Bioinformatics Authors: Allavarapu Ramya Sree K Sethumadhavan S P Tejaswi Pullakanam Purimitla Usharani Source Type: research
Sa1818 RISK FACTORS AND OUTCOMES OF AUTOIMMUNE ALOPECIA IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Yushan Pan, Evelyn Lilly, Ashwin Ananthakrishnan Tags: AGA Abstracts Source Type: research
Patch Testing and Allergic Contact Dermatitis in Patients with Lichen Planopilaris and/or Frontal Fibrosing Alopecia: A Systematic Reviewand Meta-Analysis
Dermatitis. 2024 May 6. doi: 10.1089/derm.2024.0034. Online ahead of print.NO ABSTRACTPMID:38709125 | DOI:10.1089/derm.2024.0034 (Source: Dermatitis)
Source: Dermatitis - May 6, 2024 Category: Dermatology Authors: Li-Chi Chen Chino Ogbutor Carol Spencer Ümmügülsüm Yıldız-Altay Kristen J Kelley Maryanne M Senna Source Type: research
Ruxolitinib 1.5% Topical Cream for the Treatment of Pediatric Alopecia Areata
J Drugs Dermatol. 2024 May 1;23(5):378-379. doi: 10.36849/JDD.7782.ABSTRACTAlopecia areata (AA) is a common autoimmune disorder. Although its pathogenesis is not fully understood, AA involves CD8 T cell-mediated destruction of the hair follicle. Several treatment options exist; however, there is minimal evidence in the pediatric population. Currently, there are no curative treatments for AA. The literature suggests that Janus kinase (JAK) inhibitors may be an effective treat-ment for AA, but evidence in pediatric patients is limited. Here, we report a case of severe pediatric AA treated with topical ruxolitinib, a JAK inhi...
Source: Journal of Drugs in Dermatology - May 6, 2024 Category: Dermatology Authors: Yazmeen Tembunde Chesahna Kindred Source Type: research
Eyebrow and Eyelash Loss in Patients With Cancer
J Drugs Dermatol. 2024 May 1;23(5):327-331. doi: 10.36849/JDD.8003.ABSTRACTThough it is widely acknowledged that cancer treatments cause hair loss on the scalp, there are limited data on how they affect eyebrow and eyelash hairs. Patients with eyebrow and eyelash loss, or madarosis, seek various treatment options ranging from camouflage techniques with makeup, permanent tattoos, and prescription medications. Though not yet studied in patients with cancer-induced madarosis, techniques such as scalp cooling, cryotherapy, and topical vasoconstrictors are promising preventative options. More robust research is needed to improv...
Source: Journal of Drugs in Dermatology - May 6, 2024 Category: Dermatology Authors: Lucy Rose Aliza Khuhro Abena Minta Madison Novice Taylor Novice Maryam B Lustberg Kathryn J Ruddy Elizabeth Cathcart- Rake Charles L Loprinzi Brittany Dulmage Source Type: research
Beyond the Label: Real-World Side Effects Experienced With FDA-Approved Drugs for Non-Melanoma Skin Cancers
J Drugs Dermatol. 2024 May 1;23(5):301-305. doi: 10.36849/JDD.7968.ABSTRACTWith immunotherapy historically focused on cutaneous melanoma, there has been a new wave of systemic medications available for treating non-melanoma skin cancers including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and Merkel cell carcinoma (MCC). The immune checkpoint inhibitors approved by the FDA target programmed cell death protein 1 (PD-1) and the Hedgehog (Hh) signaling pathway. These medications have expanded treatment options; however, side effects are an important consideration. We used the FDA Adverse Events Reporting Syste...
Source: Journal of Drugs in Dermatology - May 6, 2024 Category: Dermatology Authors: Advaitaa Ravipati Tejus Pradeep Keyvan Nouri Source Type: research
Patch Testing and Allergic Contact Dermatitis in Patients with Lichen Planopilaris and/or Frontal Fibrosing Alopecia: A Systematic Reviewand Meta-Analysis
Dermatitis. 2024 May 6. doi: 10.1089/derm.2024.0034. Online ahead of print.NO ABSTRACTPMID:38709125 | DOI:10.1089/derm.2024.0034 (Source: Dermatitis)
Source: Dermatitis - May 6, 2024 Category: Dermatology Authors: Li-Chi Chen Chino Ogbutor Carol Spencer Ümmügülsüm Yıldız-Altay Kristen J Kelley Maryanne M Senna Source Type: research
