Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK
CONCLUSIONS: The HZ incidence rate in Europe increased with age and varied across high-risk populations, with high rates for solid organ and stem cell transplants, cancer, and rheumatoid arthritis. Most studies were retrospective with methodological differences affecting generalizability and comparability. Future studies should stratify data by IC population, age, sex, severity, medication, and study timeframe.PMID:38656653 | DOI:10.1007/s40121-024-00963-w (Source: Herpes)
Source: Herpes - April 24, 2024 Category: Infectious Diseases Authors: Alen Marijam Nikki Vroom Amit Bhavsar Inga Posiuniene Nicolas Lecrenier Hilde Vroling Source Type: research
Systematic Literature Review on the Incidence of Herpes Zoster in Populations at Increased Risk of Disease in the EU/EEA, Switzerland, and the UK
ConclusionsThe HZ incidence rate in Europe increased with age and varied across high-risk populations, with high rates for solid organ and stem cell transplants, cancer, and rheumatoid arthritis. Most studies were retrospective with methodological differences affecting generalizability and comparability. Future studies should stratify data by IC population, age, sex, severity, medication, and study timeframe. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - April 24, 2024 Category: Infectious Diseases Source Type: research
Proposal of model for personalized early adapted cancer screening in people living with HIV: experience of "Gaetano Martino" Hospital University of Messina
Eur Rev Med Pharmacol Sci. 2024 Apr;28(7):2929-2942. doi: 10.26355/eurrev_202404_35924.ABSTRACTHuman immunodeficiency virus (HIV) infection has historically been related to the development of specific cancers, some of which are so closely linked to the infection, such as Kaposi's Sarcoma (KS), that they have earned the name Acquired Immuno-Deficiency Syndrome (AIDS)-defining cancers (ADCs). While the development of antiretroviral therapy (ART) has decreased the incidence of AIDS-defining cancers, the resulting aging of people living with HIV (PLWH) highlighted an increased occurrence of other forms of cancer. At the "Gaeta...
Source: Pharmacological Reviews - April 19, 2024 Category: Drugs & Pharmacology Authors: G F Pellican ò A Squeri G Ciappina R Squeri V I Palmara S Parisi I Campo C Saitta M Rossanese E Di Trapani S Mancuso N Catalano A Allegra G Mancuso G Murolo A Bignucolo D A Restivo P Consolo M Berretta Source Type: research
Proposal of model for personalized early adapted cancer screening in people living with HIV: experience of "Gaetano Martino" Hospital University of Messina
Eur Rev Med Pharmacol Sci. 2024 Apr;28(7):2929-2942. doi: 10.26355/eurrev_202404_35924.ABSTRACTHuman immunodeficiency virus (HIV) infection has historically been related to the development of specific cancers, some of which are so closely linked to the infection, such as Kaposi's Sarcoma (KS), that they have earned the name Acquired Immuno-Deficiency Syndrome (AIDS)-defining cancers (ADCs). While the development of antiretroviral therapy (ART) has decreased the incidence of AIDS-defining cancers, the resulting aging of people living with HIV (PLWH) highlighted an increased occurrence of other forms of cancer. At the "Gaeta...
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: G F Pellican ò A Squeri G Ciappina R Squeri V I Palmara S Parisi I Campo C Saitta M Rossanese E Di Trapani S Mancuso N Catalano A Allegra G Mancuso G Murolo A Bignucolo D A Restivo P Consolo M Berretta Source Type: research
Plans to expand African vaccine production face steep hurdles
In March 2022, when the pandemic was still raging, the messenger RNA (mRNA) company Moderna announced it would build a $500 million plant in Kenya to manufacture half a billion doses of its COVID-19 vaccine annually. “
This is major
,” Kenyan President William Ruto said at the time. The plant would help reduce Africa’s dependence on vaccines produced elsewhere, Ruto said—a situation that had turned disastrous during the pandemic—and bring economic benefits as well.
But Moderna may never break ground on the Kenya factory. On 11 April, the company said it had
“paused its efforts”
becau...
Source: Science of Aging Knowledge Environment - April 16, 2024 Category: Geriatrics Source Type: research
COVID-19 Vaccine Hesitancy Among People Living with HIV: A Systematic Review and Meta-Analysis
AbstractVaccine hesitancy is one of the top 10 threats to global health, which affects the prevalence and fatality of vaccine-preventable diseases over the world. During the COVID-19 pandemic, people living with HIV (PLWH) may have higher risks of infection, more serious complications, and worse prognosis without the protection of the COVID-19 vaccine. A systematic review and meta-analysis aiming to evaluate the prevalence of COVID-19 vaccine hesitancy among PLWH was conducted using PubMed, Embase, and Web of Science databases for studies published between January 1, 2020, and August 31, 2022. The pooled prevalence with a ...
Source: AIDS and Behavior - April 16, 2024 Category: Infectious Diseases Source Type: research
Thermal imaging and computer vision technologies for the enhancement of pig husbandry: a review
This study provides valuable insights for researchers and farmers regarding IRT application in pig production, highlighting notable approaches and the latest research findings in this field.PMID:38618025 | PMC:PMC11007457 | DOI:10.5187/jast.2024.e4 (Source: Rural Remote Health)
Source: Rural Remote Health - April 15, 2024 Category: Rural Health Authors: Md Nasim Reza Md Razob Ali None Samsuzzaman Md Shaha Nur Kabir Md Rejaul Karim Shahriar Ahmed Hyunjin Kyoung Gookhwan Kim Sun-Ok Chung Source Type: research
Thermal imaging and computer vision technologies for the enhancement of pig husbandry: a review
This study provides valuable insights for researchers and farmers regarding IRT application in pig production, highlighting notable approaches and the latest research findings in this field.PMID:38618025 | PMC:PMC11007457 | DOI:10.5187/jast.2024.e4 (Source: Rural Remote Health)
Source: Rural Remote Health - April 15, 2024 Category: Rural Health Authors: Md Nasim Reza Md Razob Ali None Samsuzzaman Md Shaha Nur Kabir Md Rejaul Karim Shahriar Ahmed Hyunjin Kyoung Gookhwan Kim Sun-Ok Chung Source Type: research
Chitosan-LeoA-DNA Nanoparticles Promoted the Efficacy of Novel LeoA-DNA Vaccination on Mice Against Helicobacter pylori
In this study, recombinant plasmids containing the LeoA gene of H. pylori are created and conjugated with chitosan nanoparticle (CSNP) to immunize BALB/c mice against the H. pylori infection. We used the online Vaxign tool to analyze the genomes of five distinct strains of H. pylori, and we chose the outer membrane as a prospective vaccine candidate. Afterward, the proteins' immunogenicity was evaluated. The DNA vaccine was constructed and then encapsulated in CSNPs. The effectiveness of the vaccine's immunoprotective effects was evaluated in BALB/c mice. Purified activated splenic CD3+ T cells are used to test the antican...
Source: Current Microbiology - April 1, 2024 Category: Microbiology Authors: Zahra Ahmadzadeh Chaleshtori Ali Asghar Rastegari Hashem Nayeri Abbas Doosti Source Type: research
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection - Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug Resistance
Med Sci Monit. 2024 Apr 1;30:e944600. doi: 10.12659/MSM.944600.ABSTRACTIn April 1984, 40 years ago, the Secretary of the US Department of Health and Human Services announced that Dr. Robert Gallo and his colleagues at the National Cancer Institute (NCI) had confirmed the cause of acquired immunodeficiency syndrome (AIDS) as a retrovirus, which became known as human immunodeficiency virus (HIV) in 1986. For the past 40 years, prevention and cure of HIV infection have been the dual 'holy grail' sought but still not achieved. By the beginning of 2024, the World Health Organization (WHO) estimated that in the past 40 years, be...
Source: Medical Science Monitor - April 1, 2024 Category: Research Authors: Dinah V Parums Source Type: research
Chitosan-LeoA-DNA Nanoparticles Promoted the Efficacy of Novel LeoA-DNA Vaccination on Mice Against Helicobacter pylori
In this study, recombinant plasmids containing the LeoA gene of H. pylori are created and conjugated with chitosan nanoparticle (CSNP) to immunize BALB/c mice against the H. pylori infection. We used the online Vaxign tool to analyze the genomes of five distinct strains of H. pylori, and we chose the outer membrane as a prospective vaccine candidate. Afterward, the proteins' immunogenicity was evaluated. The DNA vaccine was constructed and then encapsulated in CSNPs. The effectiveness of the vaccine's immunoprotective effects was evaluated in BALB/c mice. Purified activated splenic CD3+ T cells are used to test the antican...
Source: Current Microbiology - April 1, 2024 Category: Microbiology Authors: Zahra Ahmadzadeh Chaleshtori Ali Asghar Rastegari Hashem Nayeri Abbas Doosti Source Type: research
Sexual behaviour and STIs among MSM living with HIV in the PrEP era: the French ANRS PRIMO cohort study
CONCLUSIONS: Implementation of TasP and more recently PrEP has led to major changes in the sexual behaviour of MSM with HIV. ICU has become overwhelmingly prevalent, PrEP use by the partner increasingly being the reported reason for ICU, behind TasP, which remains the main reason. Characteristics of MSM at the time of diagnosis of HIV have changed, with fewer number of sexual partners today than in 2014, which must lead to broaden the indications for PrEP prescription. STIs incidence remains high in MSM with HIV and requires improvements in screening and prevention methods such as pre- or post-exposition antibiotics or vac...
Source: Journal of the International AIDS Society - March 11, 2024 Category: Infectious Diseases Authors: Virginie Baltes Paul de Boissieu Karen Champenois Louise Luan R émonie Seng Asma Essat Sophie Novelli Bruno Spire Jean-Michel Molina C écile Goujard Laurence Meyer ANRS PRIMO cohort study group Source Type: research
Sexual behaviour and STIs among MSM living with HIV in the PrEP era: the French ANRS PRIMO cohort study
CONCLUSIONS: Implementation of TasP and more recently PrEP has led to major changes in the sexual behaviour of MSM with HIV. ICU has become overwhelmingly prevalent, PrEP use by the partner increasingly being the reported reason for ICU, behind TasP, which remains the main reason. Characteristics of MSM at the time of diagnosis of HIV have changed, with fewer number of sexual partners today than in 2014, which must lead to broaden the indications for PrEP prescription. STIs incidence remains high in MSM with HIV and requires improvements in screening and prevention methods such as pre- or post-exposition antibiotics or vac...
Source: Journal of the International AIDS Society - March 11, 2024 Category: Infectious Diseases Authors: Virginie Baltes Paul de Boissieu Karen Champenois Louise Luan R émonie Seng Asma Essat Sophie Novelli Bruno Spire Jean-Michel Molina C écile Goujard Laurence Meyer ANRS PRIMO cohort study group Source Type: research
