Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach
Ocul Surf. 2022 Apr 21:S1542-0124(22)00029-5. doi: 10.1016/j.jtos.2022.04.003. Online ahead of print.ABSTRACTAcanthamoeba keratitis (AK) is a severe cause of infectious keratitis and presents a significant clinical challenge. Recent literature regarding AK epidemiology, diagnosis, treatment modalities, and prognosis is reviewed and synthesized to propose an algorithmic protocol for AK management. Globally, AK outbreaks in developed countries are ongoing, and AK rates have increased. Moreover, current outbreaks may carry a worse prognosis than prior outbreaks. Despite identification of contact lens solutions implicated in A...
Source: The Ocular Surface - April 24, 2022 Category: Opthalmology Authors: Aaron R Kaufman Elmer Y Tu Source Type: research
Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach
Ocul Surf. 2022 Apr 21:S1542-0124(22)00029-5. doi: 10.1016/j.jtos.2022.04.003. Online ahead of print.ABSTRACTAcanthamoeba keratitis (AK) is a severe cause of infectious keratitis and presents a significant clinical challenge. Recent literature regarding AK epidemiology, diagnosis, treatment modalities, and prognosis is reviewed and synthesized to propose an algorithmic protocol for AK management. Globally, AK outbreaks in developed countries are ongoing, and AK rates have increased. Moreover, current outbreaks may carry a worse prognosis than prior outbreaks. Despite identification of contact lens solutions implicated in A...
Source: The Ocular Surface - April 24, 2022 Category: Opthalmology Authors: Aaron R Kaufman Elmer Y Tu Source Type: research
Case Report: Novel Patient Training Technique for the Application and Removal of Scleral Lenses
CONCLUSIONS: A novel piggyback training technique can be used to overcome obstacles during the scleral lens application and removal training process.PMID:35413040 | DOI:10.1097/OPX.0000000000001905 (Source: Herpes)
Source: Herpes - April 12, 2022 Category: Infectious Diseases Authors: Alan Kwok Stephanie Derby Dina Zeldin Daniel Brocks Source Type: research
Case Report: Novel Patient Training Technique for the Application and Removal of Scleral Lenses
CONCLUSIONS: A novel piggyback training technique can be used to overcome obstacles during the scleral lens application and removal training process.PMID:35413040 | DOI:10.1097/OPX.0000000000001905 (Source: Herpes)
Source: Herpes - April 12, 2022 Category: Infectious Diseases Authors: Alan Kwok Stephanie Derby Dina Zeldin Daniel Brocks Source Type: research
Potential anti-acanthamoebic effects through inhibition of CYP51 by novel quinazolinones
This report presents several potential lead compounds belonging to quinazolinone derivatives for drug discovery against Acanthamoeba infections.PMID:35378058 | DOI:10.1016/j.actatropica.2022.106440 (Source: Acta Tropica)
Source: Acta Tropica - April 4, 2022 Category: Infectious Diseases Authors: Usman Ahmed Keat-Yie Ho Samson Eugin Simon Syed Muhammad Saad Seng-Kai Ong Areeba Anwar Kuan Onn Tan Nanthini Sridewi Khalid Mohammed Khan Naveed Ahmed Khan Ayaz Anwar Source Type: research
Potential anti-acanthamoebic effects through inhibition of CYP51 by novel quinazolinones
This report presents several potential lead compounds belonging to quinazolinone derivatives for drug discovery against Acanthamoeba infections.PMID:35378058 | DOI:10.1016/j.actatropica.2022.106440 (Source: Acta Tropica)
Source: Acta Tropica - April 4, 2022 Category: Infectious Diseases Authors: Usman Ahmed Keat-Yie Ho Samson Eugin Simon Syed Muhammad Saad Seng-Kai Ong Areeba Anwar Kuan Onn Tan Nanthini Sridewi Khalid Mohammed Khan Naveed Ahmed Khan Ayaz Anwar Source Type: research
Potential anti-acanthamoebic effects through inhibition of CYP51 by novel quinazolinones
This report presents several potential lead compounds belonging to quinazolinone derivatives for drug discovery against Acanthamoeba infections.PMID:35378058 | DOI:10.1016/j.actatropica.2022.106440 (Source: Acta Tropica)
Source: Acta Tropica - April 4, 2022 Category: Infectious Diseases Authors: Usman Ahmed Keat-Yie Ho Samson Eugin Simon Syed Muhammad Saad Seng-Kai Ong Areeba Anwar Kuan Onn Tan Nanthini Sridewi Khalid Mohammed Khan Naveed Ahmed Khan Ayaz Anwar Source Type: research
An Update on the Initial Treatment of Acanthamoeba Keratitis
No abstract available (Source: International Ophthalmology Clinics)
Source: International Ophthalmology Clinics - March 28, 2022 Category: Opthalmology Tags: Original Articles Source Type: research
Clinical and molecular diagnosis of Acanthamoeba keratitis in contact lens wearers in southern Brazil reveals the presence of an endosymbiont
Parasitol Res. 2022 Feb 23. doi: 10.1007/s00436-022-07474-y. Online ahead of print.ABSTRACTAcanthamoeba keratitis (AK) is an infection that is mostly observed in contact lens wearers. It is often misdiagnosed causing delays in the administration of the correct treatment. The aim of this study was to report the outcome of clinical and molecular diagnosis of AK cases during the summer of 2019 in the southern region of Brazil. Three suspected cases of AK were discovered after an ophthalmic examination at a public hospital in the city of Porto Alegre. These cases were then confirmed through laboratory diagnosis (cell culture a...
Source: Cell Research - February 23, 2022 Category: Cytology Authors: Denise Leal Dos Santos Veridiana Gomes Virginio Francisco Kercher Bert é Karina Rodrigues Lorenzatto Diane Ruschel Marinho Sergio Kwitko Claudete In ês Locatelli Eduarda Correa Freitas Marilise Brittes Rott Source Type: research
Report of rare genotypes of Acanthamoeba from soil source of the Payeh Maga Highland forest, North-eastern Sarawak, Malaysia
Acta Trop. 2022 Feb 16:106372. doi: 10.1016/j.actatropica.2022.106372. Online ahead of print.ABSTRACTPathogenic Acanthamoeba species are the causative agents of Acanthamoeba keratitis and granulomatous amoebic encephalitis. Members of this amoeba genus are ubiquitous in the environments. In Malaysia, most environmental studies performed to date have targeted the detection and characterisation of Acanthamoeba sp. in different water sources, dust and soil samples collected near human habitats. However, no local study has yet to examine these amoebae in a forest, an isolated terrestrial environment, where human activity is re...
Source: Acta Tropica - February 19, 2022 Category: Infectious Diseases Authors: Li-Li Chan Hiu-Ching Toh Kantiya Jaikwang Ee-Mun Loo Jia-Haw Wong Yun-Khoon Liew Kian-Huat Ong Soo-Shen Ooi Source Type: research
