Total Anterior Staphyloma Secondary to Acanthamoeba Keratitis
This study reports the clinical and histopathological findings and subsequent management of a 27-year-old healthy female patient who developed total anterior staphyloma after poor compliance with treatment for clinically diagnosed acanthamoeba keratitis. She underwent a successful evisceration with good long-term results. This case highlights that total anterior staphyloma may also result from untreated keratitis which is not fungal in origin. In cases of fungal and acanthamoeba keratitis, patient compliance with both treatment and follow-up is paramount to avoid vision-threatening sequelae that present significant challen...
Source: Eye and Contact Lens: Science and Clinical Practice - January 27, 2022 Category: Opthalmology Tags: Case Report Source Type: research
In Vitro Activity of Pentamidine Isethionate against Trophozoite and Cyst of < em > Acanthamoeba < /em >
CONCLUSION: Pentamidine isethionate exhibited an inhibitory effect on trophozoite and cyst. Given that the trophozoicidal activity of the drug is in the safe dose, it could be suggested as an alternative in patients with AK; however, further investigation is needed in an animal model to confirm the data.PMID:35082884 | PMC:PMC8710197 | DOI:10.18502/ijpa.v16i4.7868 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - January 27, 2022 Category: Parasitology Authors: Massoud Behnia Alireza Latifi Mostafa Rezaian Sharmin Kharazi Mehdi Mohebali Setayesh Yasami Shiva Saghafi Reza Chahardoli Narges Anasori Hakimeh Torkian Mohammad Soleimani Maryam Niyyati Elham Kazemirad Source Type: research
