Effects of long-term antiepileptic therapy on carotid artery intima-media thickness

Conclusion: Children on long-term monotherapy with valproate, phenytoin, and levetiracetam have significantly abnormal CIMT. This might be associated with atherosclerotic changes, and these children may require close follow-up to prevent cardiovascular and cerebrovascular risks.

Source: Journal of Pediatric Neurosciences - December 3, 2021 Category: Neuroscience Authors: Vipul U Kolekar Seema P Sindgikar Raghuraj Uppoor Dhrithiman Shetty KM Vijaya Shenoy Source Type: research