Common mtDNA variations at C5178a and A249d/T6392C/G10310A decrease the risk of severe COVID-19 in a Han Chinese population from Central China

ConclusionsThis is the first study to explore the association of mtDNA variants with individual ’s risk of developing severe COVID-19. Based on the case–control study, we concluded that the common mtDNA variants at C5178a and A249d/T6392C/G10310A might contribute to an individual’s resistance to developing severe COVID-19, whereas A4833G, A4715G, T3394C and G5417A/C16257a/C16261T might i ncrease an individual’s risk of developing severe COVID-19.
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research