Genes, Vol. 12, Pages 1152: Variant Transthyretin Amyloidosis (ATTRv) in Hungary: First Data on Epidemiology and Clinical Features

Conclusions: As TTR genotype influences the phenotype and clinical course of ATTRv, it is important to know the regional data. In Hungary, ATTRHis88Arg and ATTRIle107Val are the most common mutations in ATTRv, both presenting with mixed phenotype, but the median age at the time of the diagnosis is 9 years lower in patients with ATTRHis88Arg than in patients with ATTRIle107Val.

Source: Genes - July 28, 2021 Category: Genetics & Stem Cells Authors: Zolt án Pozsonyi Gergely Pesk ó Hedvig Tak ács Dorottya Csuka Vikt ória Nagy Ágnes Szilágyi Lidia Hategan Bal ázs Muk Be áta Csányi No émi Nyolczas L ívia Dézsi Judit M ária Molnár Anita Csillik Katalin R évész B éla Iványi Fruzsina Szab Tags: Article Source Type: research