Increased telomere length in patients with frontotemporal dementia syndrome

Telomeres are repetitive DNA sequences of TTAGGG at the ends of chromosomes. Many studies have shown that telomere shortening is associated with aging-related diseases, such as cardiovascular diseases, hypertension, diabetes, cancer, and various neurodegenerative diseases, including Alzheimer's disease, vascular dementia, Parkinson's disease, and dementia with Lewy bodies. However, changes in telomere length (TL) in patients with frontotemporal dementia (FTD) syndrome are unclear. Accordingly, in this study, we assessed TL in blood samples from patients with FTD syndrome.

Source: Journal of the Neurological Sciences - July 3, 2021 Category: Neurology Authors: Eun-Joo Kim, Seong-Ho Koh, Jungsoon Ha, Duk L. Na, Sang Won Seo, Hee-Jin Kim, Kyung Won Park, Jae-Hong Lee, Jee Hoon Roh, Jay C. Kwon, Soo Jin Yoon, Na-Yeon Jung, Jee H. Jeong, Jae-Won Jang, Hee-Jin Kim, Kee Hyung Park, Seong Hye Choi, SangYun Kim, Young Tags: Clinical short communication Source Type: research