Cancers, Vol. 13, Pages 1469: The Epithelial –Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer

In conclusion, the SNAI1/let-7 axis is an important component of stemness pathways in cancer cells, and this study provides a rationale for future work examining this axis as a potential target for cancer stem cell-specific therapies.

Source: Cancers - March 23, 2021 Category: Cancer & Oncology Authors: Hanmin Wang Evgeny Chirshev Nozomi Hojo Tise Suzuki Antonella Bertucci Michael Pierce Christopher Perry Ruining Wang Jeffrey Zink Carlotta A. Glackin Yevgeniya J. Ioffe Juli J. Unternaehrer Tags: Article Source Type: research