Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease

CONCLUSIONS: The evidence examined was determined to be of low certainty and suggests that prophylactic penicillin significantly reduces risk of pneumococcal infection in children with homozygous SCD, and is associated with minimal adverse reactions. Further research may help to determine the ideal age to safely withdraw penicillin.PMID:33724440 | DOI:10.1002/14651858.CD003427.pub5
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research