Inhibition of semaphorin 4D enhances chemosensitivity by increasing 5-fluorouracile-induced apoptosis in colorectal cancer cells.

This study implicates that the silencing of SEMA4D by siRNA promotes the chemosensitivity of SW48 cells to 5-FU and it may be a potential therapeutic agent for colon cancer therapy. PMID: 32888127 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32888127?dopt=Abstract

Source: Molecular Biology Reports - September 3, 2020 Category: Molecular Biology Authors: Rashidi G, Rezaeepoor M, Mohammadi C, Solgi G, Najafi R Tags: Mol Biol Rep Source Type: research