Downregulation of DNAJC10 (ERDJ5) is associated with poor survival in breast cancer.

CONCLUSIONS: In the light of previous knowledge regarding the role of DNAJC10 in carcinogenesis, findings of this study suggest that DNAJC10 is a potential diagnostic/prognostic biomarker and tumor suppressor candidate for breast cancer. Epigenetic factors other than promoter methylation could contribute to the downregulation of DNAJC10 expression.
PMID: 31902119 [PubMed - as supplied by publisher]

Source: Breast Cancer - January 3, 2020 Category: Cancer & Oncology Authors: Acun T, Senses KM Tags: Breast Cancer Source Type: research