Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery.

CONCLUSIONS: Evidence was insufficient to allow review authors to conclude that statin use resulted in either a reduction or an increase in any of the outcomes examined. The existing body of evidence leaves questions about the benefits of perioperative use of statins for vascular surgery unanswered. Widespread use of statins in the target population means that it may now be difficult for researchers to undertake the large RCTs needed to demonstrate any effect on the incidence of postoperative cardiovascular events. However, participant-reported outcomes have been neglected and warrant further study. PMID: 23824754 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23824754?dopt=Abstract

Source: Cochrane Database of Systematic Reviews - July 3, 2013 Category: Journals (General) Authors: Sanders RD, Nicholson A, Lewis SR, Smith AF, Alderson P Tags: Cochrane Database Syst Rev Source Type: research