Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: think out of the box!

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western societies and a major cause of hepatic disease worldwide. Its more severe type, namely nonalcoholic steatohepatitis (NASH), may result in the development of cirrhosis and hepatocellular carcinoma. NAFLD, and especially NASH, are also associated with increased cardiovascular morbidity and mortality. Type 2 diabetes mellitus (T2DM) predisposes to NAFLD development and progression via insulin resistance and hyperglycemia.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research