Mechanism Underlying the Formation of a Cluster of Metabolic Syndrome.

CONCLUSIONS: The paper demonstrates that the autonomic dysfunction of nervous system (on a par with insulin resistance) is the main link in the development of MetS. This provides the basis for including the mentioned states - cardiac autonomic neuropathy, lower urinary tract symptoms and gastroesophageal reflux disease - into the MetS cluster. PMID: 31589129 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

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Conclusions: We found that perceived stigma in health care settings was a potential barrier to good health. Prior studies have illustrated that negative health outcomes are common for patients who avoid or delay care; thus, the unfortunate conclusion is that even in a diverse, heterogeneous community, stigma persists and may negatively affect well-being. Therefore, eliminating stigma in clinical settings should be a top priority for health care providers and public health professionals seeking to improve health equity.
Source: Medical Care - Category: Health Management Tags: Original Articles Source Type: research
[VOA] On the eve of World Diabetes Day, November 14, the World Health Organization is launching a new initiative it believes will allow greater access to life-saving insulin at lower prices for a greater number of people suffering from diabetes.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
(Duke-NUS Medical School) World's foremost society of kidney specialists highlights Singapore-led DYNAMO study that aims to improve understanding of diabetic kidney disease (DKD) complications and reduce DKD prevalence in Singapore by 30% over 5 years. Study is led by Duke-NUS Medical School Dean, Prof. Thomas Coffman.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(European Society of Cardiology) Women are most affected by the vascular complications of diabetes -- a situation likely to escalate in the coming decades, reports a paper published on World Diabetes Day in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Publication date: Available online 12 November 2019Source: Brain, Behavior, and ImmunityAuthor(s): Célia Fourrier, Camille Kropp, Agnès Aubert, Julie Sauvant, Carole Vaysse, Jean-Michel Chardigny, Sophie Layé, Corinne Joffre, Nathalie CastanonAbstractMetabolic syndrome represents a major risk factor for severe comorbidities such as cardiovascular diseases or diabetes. It is also associated with an increased prevalence of emotional and cognitive alterations that in turn aggravate the disease and related outcomes. Identifying therapeutic strategies able to improve those alterations is therefore a major s...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
This study investigated the therapeutic outcomes of LDJB-SG and predictors of type 2 diabetes (T2D) remission in Chinese patients with a body mass index (BMI) of 20 to 32.5 kg/m2. SETTING: A university hospital. METHODS: This retrospective study included 28 T2D patients with a BMI of 20 to 32.5 kg/m2 who underwent LDJB-SG. T2DM remission, weight loss, postoperative nutrition status, and complications at 1- and 3-year follow-up were assessed. Remission of T2DM was defined as a fasting blood glucose
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - Category: Surgery Authors: Tags: Surg Obes Relat Dis Source Type: research
  (Image courtesy of MedAutonomic) MedAutonomic said today it has successfully implanted a brain neuromodulation device, the Phoenix, into the stomach wall of a human through an innovative digestive endoscopic procedure. Powered without a battery, the Phoenix sends signals to the limbic system to reset an imbalance in the autonomic nervous system to treat metabolic syndrome and functional diseases such as type-2 diabetes, hypertension, and gastroesophageal reflux disease, according to a company statement. The company developed a piezoelectric energy harvesting system (PEHS) to power the Phoenix.  The PEHS is...
Source: Mass Device - Category: Medical Devices Authors: Tags: Bioelectronic Medicine Biotech Blog Diabetes Implants Neuromodulation/Neurostimulation Research & Development medautonomic Source Type: news
ConclusionRYGB results in better weight loss compared to SG in Asians, but the rate of T2DM resolution/improvement and improvement of hypertension appears to be similar. In Asian patients without symptoms of gastro-esophageal reflux disease in whom metabolic surgery is performed mainly for T2DM and metabolic syndrome, SG may be the surgery of choice.
Source: Obesity Surgery - Category: Surgery Source Type: research
Publication date: June 2016 Source:Cancer Epidemiology, Volume 42 Author(s): Jennifer Drahos, Lin Li, Susan S. Jick, Michael B. Cook Gastroesophageal reflux disease (GERD) causes local chronic inflammation that increases risks of Barrett’s esophagus (BE) and esophageal adenocarcinoma (EA), yet symptomatic GERD is absent in approximately half of all such patients. Obesity exacerbates GERD and is also a component of metabolic syndrome (MetS). We evaluated the hypothesis that MetS is a GERD-independent mechanism by which obesity is associated with increased risks of BE and EA using data from the UK Clinical Practi...
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
Publication date: June 2016 Source:Cancer Epidemiology, Volume 42 Author(s): Jennifer Drahos, Lin Li, Susan S. Jick, Michael B. Cook Gastroesophageal reflux disease (GERD) causes local chronic inflammation that increases risks of Barrett’s esophagus (BE) and esophageal adenocarcinoma (EA), yet symptomatic GERD is absent in approximately half of all such patients. Obesity exacerbates GERD and is also a component of metabolic syndrome (MetS). We evaluated the hypothesis that MetS is a GERD-independent mechanism by which obesity is associated with increased risks of BE and EA using data from the UK Clinical Practi...
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
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