Association of non-alcoholic fatty liver disease with microvascular complications of type 2 diabetes

Non-alcoholic fatty liver disease (NAFLD) is a complex multiorgan disorder in which subtle interpatient genetic variations and environmental factors interact to determine disease phenotype, progression, and natural history [1]. It is already known that NAFLD increases the risks for the development and/or progression of type 2 diabetes (T2D) [2,3] and cardiovascular disease (CVD) [1,4]. From a clinical standpoint, the bidirectional relationships among NAFLD, T2D, and CVD produce hepatic fibrogenesis, insulin resistance, and CVD manifestations of the metabolic syndrome (MetS) [1].

Source: Primary Care Diabetes - April 30, 2019 Category: Primary Care Authors: Mohsen Afarideh, Zahra Aryan, Alireza Ghajar, Morsaleh Ganji, Fatemeh Ghaemi, Mohammad Saadat, Behnam Heidari, Jeffrey I. Mechanick, Alireza Esteghamati Tags: Original research Source Type: research