Molecular influenza surveillance at a tertiary university hospital during four consecutive seasons (2012-2016) in Catalonia, Spain.

CONCLUSIONS: The circulation of drifted A(H3N2) strains during the 2014-2015 season was related to the high hospitalisation rate due to the mismatch with the vaccine strains. The predominance of a FLUBV lineage not included in the trivalent influenza vaccine during the 2015-2016 season highlights the need to use a tetravalent influenza vaccine. Virological surveillance of viral variants carrying protein changes that alter tropism and susceptibility to antivirals features should be strengthened in hospital settings.
PMID: 30926297 [PubMed - as supplied by publisher]

Source: Vaccine - March 26, 2019 Category: Allergy & Immunology Authors: Andrés C, Peremiquel-Trillas P, Gimferrer L, Piñana M, Codina MG, Rodrigo-Pendás JÁ, Campins-Martí M, Carmen Martín M, Fuentes F, Rubio S, Pumarola T, Antón A Tags: Vaccine Source Type: research