Bilateral Herpes Simplex Virus-related Peripheral Ulcerative Keratitis Leading to Corneal Perforation in a Patient with Primary Herpes Simplex Virus Infection.

Conclusion: In cases of PUK, differential diagnosis should include infectious and autoimmune diseases. Primary HSV should also be considered as a potential cause of this form of keratitis, which, if left untreated, can lead to devastating outcomes. To our knowledge, this is the first published case of bilateral PUK caused by primary HSV-1 infection. PMID: 30820293 [PubMed]
Source: Journal of Ophthalmic and Vision Research - Category: Opthalmology Tags: J Ophthalmic Vis Res Source Type: research

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ConclusionPresumed higher anti-leukemic activity of RIC versus NMA conditioning did not translate into better outcomes after alloHSCT, but better remission status prior to conditioning did. Effective pathway inhibitor-based salvage therapies combined with NMA conditioning might thus represent the most attractive contemporary approach for alloHSCT for patients with CLL.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
This study analyzed PCT and CRP levels of 214 pediatric patients with a median age of 8.5  years (0.4–17.8 years) undergoing allogeneic HSCT with respect to major TRAE.Results26 patients (12.1%) did not experience TRAE (control group), and 188 (87.9%) experienced median 2 (range 1 –4) TRAE. Median CRP and PCT were highly and significantly increased during sepsis/SIRS and bacteremia (17.24 mg/dl | 6.30 ng/ml;p 
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 18 October 2019Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Jean-Stéphane David, Kenji Inaba
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 18 October 2019Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Onur Koyuncu, Sedat Hakimoğlu, Sibel Tugce Polat, Merve Yazıcı Kara
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Reena Goswami1, Gayatri Subramanian2, Liliya Silayeva1, Isabelle Newkirk1, Deborah Doctor1, Karan Chawla2, Saurabh Chattopadhyay2, Dhyan Chandra3, Nageswararao Chilukuri1 and Venkaiah Betapudi1,4* 1Neuroscience Branch, Research Division, United States Army Medical Research Institute of Chemical Defense, Aberdeen, MD, United States 2Department of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States 3Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States 4Department of Physiology and Biophysics, Case Western Reserve University, Clev...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with ...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
​BY NATALIE CAZEAU, ​MSC; ERICA ROMAN HERNANDEZ; KINZA IJAZ; AMY SCHEUERMANN; AHMED RAZIUDDIN, MDA 43-year-old man presented to the ED with a rash in a C7 dermatomal pattern that was burning and painful. The patient said the rash began three weeks before the ED visit as a group of little blisters on his right upper back and extending down his right arm. The patient was worried and in mild distress as the rash continued to burn, and he reported numbness to the area. He mentioned he had received the shingles vaccine in the past.​The patient's rash was yellow, crusty, and tender upon palpation. The area was hyperke...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Naturopathy and naturopaths are a fairly frequent topic on this blog —and for very good reason. If there is an example of a pseudomedical " discipline " that has been gaining undeserved " respectability, " it's naturopathy. It's licensed in all too many states, and physicians who have fallen under the spell of so-called " integrative medicine, " a specialty that rebrands science-based lifestyle medical interventions as somehow " alternative " or " integrative " and uses them as a vessel to " integrate " quackery into medicine, seem to have a special affinity...
Source: Respectful Insolence - Category: Surgery Authors: Source Type: blogs
Have you ever wondered how you manage to get through a particularly stressful period – whether it's an intense deadline at work, final exams in school or a spate of holiday houseguests – only to get sick after the stress has lifted? It's not a fluke. It's a phenomenon that's often referred to as "the let-down effect," a pattern in which people come down with an illness or develop flare-ups of a chronic condition not during a concentrated period of stress but after it dissipates, explains psychologist Marc Schoen, an assistant clinical professor of medicine at th...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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