Depth Electrodes or Digital Biomarkers? The future of mood monitoring

Stereoelectroencephalography (SEEG) vs.Mindstrong HealthMood Monitoring via Invasive Brain Recordings or Smartphone SwipesWhich Would You Choose?That's not really a fair question. The ultimate goal of invasive recordings is one of direct intervention, by delivering targeted brain stimulation as a treatment. But first you have to establish a firm relationship between neural activity and mood. Well, um, smartphone swipes (the way you interact with your phone) aim to establish a firm relationship between your “digital phenotype” and your mood. And then refer you to an app for a precision intervention. Or to your therapist / psychiatrist, who has to buy into use of the digital phenotyping software.On the invasive side of the question,DARPA hasinvested heavily in deep brain stimulation (DBS) as a treatment formany disorders– Post-Traumatic Stress Disorder (PTSD), Major Depression, Borderline Personality Disorder, General Anxiety Disorder, Traumatic Brain Injury, Substance Abuse/Addiction, Fibromyalgia/Chronic Pain, andmemory loss. None of the work has led to effective treatments (yet?), but the DARPA research model has established large centers of collaborating scientists who record from the brains of epilepsy patients. And a lot of very impressive papers have emerged – somepromising, othersnot so much.One recent study (Kirkby et al., 2018) used machine learning to discover brain networks that encode variations in self-reported mood. The metric was coherenc...
Source: The Neurocritic - Category: Neuroscience Authors: Source Type: blogs

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ConclusionsOur study found that the decision-making process in ESRD is multifactorial and involves not only medical factors, but also assessment of social factors, quality of life, and patient/family preference. Bettering our understanding of this decision-making process will positively impact patients and families through more informed decision-making.
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
Resumen A pesar de que son ampliamente conocidos los perfiles de utilizaci ón de las benzodiazepinas (BZD) y los riesgos asociados, este conocimiento no ha conducido a visibles transformaciones que mejoren la seguridad de los tratamientos y la salud de los pacientes. Por tanto, es necesaria una mejor compresión del contexto de su utilización, con el fin de implementar a cciones educativas eficaces, tomar decisiones clínicas pertinentes y perfeccionar su regulación en los servicios de salud. Este artículo se propone caracterizar el perfil de utilización de benzodiazepinas en ...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
ABSTRACT OBJECTIVE To evaluate the factors associated with tooth loss in adults from the position and number of teeth lost in the dental arches. METHODS This is a cross-sectional, population-based study with adults participating in the epidemiological survey of oral health of S ão Paulo in 2015. The outcome of the study was tooth loss, assessed by the proposed classification, namely: I) lost up to 12 back teeth; II) lost up to 12 teeth (including front teeth); and III) lost more than 12 teeth. A four-block analysis was conducted, supported by a conceptual theoretical mode l adapted for tooth loss. For the multinomia...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
ConclusionA long history of shoulder pain that is not responsive to conservative management in young patients should raise the suspicion of an "OO", and physicians should be encouraged to use early advanced imaging modalities in order to confirm it.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionGiven the increasing number of such surgeries performed the recognition of acute and chronic complications, and their optimal management is of great importance. Although performing a Roux-en-Y fistulojejunostomy was recommended in the literature, conservative and endoscopic treatment should be considered before.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We present this case for the uniqueness of the bilateral ovarian pathology as well as to show that robotic-assisted resection of ovarian tumors in certain children is safe and feasible.
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
Publication date: Available online 9 December 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): I Laffont, J Froger, C Jourdan, K Bakhti, LEH Van Dokkum, A Gouaich, HY Bonnin, P Armingaud, A Jaussent, MC Picot, E Le Bars, A Dupeyron, C Arquizan, A Gelis, D MottetAbstractBackground. Few rehabilitation methods have proven their efficacy in increasing sensori-motor recovery and/or function of the upper limb (UL) after stroke. Video games (VGs) are promising tools in this indication.Objective. To compare UL rehabilitation by using VGs and conventional rehabilitation (CR) in patients with sub-acute stroke.Des...
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: Available online 9 December 2019Source: Social Science &MedicineAuthor(s): Maddalena Canna, Rebecca SeligmanAbstractFunctional Neurological Disorder (FND), otherwise known as Conversion Disorder, is characterized by abnormal sensory or motor symptoms that are determined to be “incompatible” with neurological disease. FND patients are a challenge for contemporary medicine. They experience high levels of distress, disability, and social isolation, yet a large proportion of those treated do not get better. Patients with FNDs are often misdiagnosed and suffer from stigma, dysfunctional medical...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
ConclusionsThe findings highlight the acceptability of physical activity as a mental health intervention tool within a post-secondary context. Importantly the results provide implications for developing strategies to incorporate physical activity as an acceptable support method within mental health services.
Source: Mental Health and Physical Activity - Category: Psychiatry & Psychology Source Type: research
Insomnia and co-existing sleeplessness and musculoskeletal pain were inversely related to long-term recovery from chronic low back pain, a study found; relieving sleep problems may improve recovery.Medscape Medical News
Source: Medscape FamilyMedicine Headlines - Category: Primary Care Tags: Internal Medicine News Source Type: news
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