Depth Electrodes or Digital Biomarkers? The future of mood monitoring

Stereoelectroencephalography (SEEG) vs.Mindstrong HealthMood Monitoring via Invasive Brain Recordings or Smartphone SwipesWhich Would You Choose?That ' s not really a fair question. The ultimate goal of invasive recordings is one of direct intervention, by delivering targeted brain stimulation as a treatment. But first you have to establish a firm relationship between neural activity and mood. Well, um, smartphone swipes (the way you interact with your phone) aim to establish a firm relationship between your “digital phenotype” and your mood. And then refer you to an app for a precision intervention. Or to your therapist / psychiatrist, who has to buy into use of the digital phenotyping software.On the invasive side of the question,DARPA hasinvested heavily in deep brain stimulation (DBS) as a treatment formany disorders– Post-Traumatic Stress Disorder (PTSD), Major Depression, Borderline Personality Disorder, General Anxiety Disorder, Traumatic Brain Injury, Substance Abuse/Addiction, Fibromyalgia/Chronic Pain, andmemory loss. None of the work has led to effective treatments (yet?), but the DARPA research model has established large centers of collaborating scientists who record from the brains of epilepsy patients. And a lot of very impressive papers have emerged – somepromising, othersnot so much.One recent study (Kirkby et al., 2018) used machine learning to discover brain networks that encode variations in self-reported mood. The metric was coherence between amyg...
Source: The Neurocritic - Category: Neuroscience Authors: Source Type: blogs