Precise hepatectomy in the treatment of patients with primary liver cancer.

Precise hepatectomy in the treatment of patients with primary liver cancer. J Biol Regul Homeost Agents. 2018 Jan 18;33(1): Authors: Chen SW, Xia HX, Fan QQ, Xie AW, Yu Y Abstract Obesity is an epidemic issue associated with low-grade inflammation and in most of the cases with poor iron condition that influences nearly every community. The present research experiment was designed to inspect the consequences of obesity on the micro architecture of heart and kidney tissues as well as on the expression of mRNA of some hepatic genes like Hepcidin, Transferrin and TNF-α in association with their role in iron regulation and proinflammatory responses in the body. Two tentative groups of Rattus norvegicus (each supplied with different proportions of fat in their food) and one control group were analysed. After a period of sixteen weeks, the rats were dissected and their organs, liver, heart and kidneys, were excised and preserved accordingly. Histological analysis of heart tissues of obese rats showed hemorrhagic condition along with interstitium widening and interstitial inflammatory condition (myocarditis) and also necrosis of some myocardial fibers. Microanalysis of kidney tissues of obese rats showed glomerular distortion, glomerular basement membrane thickening and enlargement of Bowman's capsule along with mesangial expansion. mRNA expressional studies of some hepatic genes of the obese rats showed significant elevation in the express...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research