Cases of Extra- Medullary Myeloma Presenting As Liver Infiltrates: A Single Community Hospital Experience

Conclusion:EMM with liver metastasis as initial presentation is rare. Since the low incidence of EMM there are no specific treatment guidelines. There are no clear prognostication factors for EMM. Patients are treated in same way as MM. The current initial treatment relies on whether the patient is a transplant candidate or not.Our first patient showed a good response to treatment. However the second patient had primary refractory disease. Given his young age more intensive chemotherapy like VDT-PACE is a good choice If necessary, should be followed by a autologous transplantation or even allogenic transplantation and/ or involving CAR T- cell therapy.A better understanding of how myeloma cells grow and thrive, as well as the biology of extramedullary tumors, is needed in order to develop better strategies for the treatment of EMM in future.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 653. Myeloma: Therapy, excluding Transplantation Source Type: research