Intranasal coinfection model allows for assessment of protein vaccines against nontypeable Haemophilus influenzae in mice.

CONCLUSION: The results from this study suggest that our NTHi AOM coinfection model is useful for assessing protein vaccines. PMID: 30136923 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research

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This study aims to reflect on the process of adoption of the preprints publication model, briefly delimiting its history and current use by the national and the international scientific community. Departing from the literature and a consultation of preprint repositories, this reflection intends to highlight the main challenges that preprint implementation will face in the Nursing area, along with its specificities. While considering its benefits for scientific dissemination, this study points out the difficulties that may arise from the implementation of mostly north-American science models in a peripheral country such as ...
Source: Revista da Escola de Enfermagem da USP - Category: Nursing Source Type: research
Researchers have developed a self-cleaning plastic wrap that repels bacteria -- and could be used to prevent the transfer of antibiotic resistant superbugs, and other forms of dangerous bacteria.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Ceribell Inc., the company that set out to simplify bedside electroencephalogram (EEG) monitoring with its Ceribell Rapid Response EEG and took home the 2019 Medical Design Excellence Awards Best-in-Show award, has just launched Clarity, a new 24/7 bedside EEG monitoring and alerting technology. The company made the announcement at the American Epileptology Society Annual Meeting. Ceribell Rapid Response EEG was designed to ease EEG setup and triage for patients with suspicion of seizure, and application does not require an EEG technician. In addition to winning the MDEA Best in Show, the system was also recognized with a ...
Source: MDDI - Category: Medical Devices Authors: Tags: Software Source Type: news
Publication date: 14–20 December 2019Source: The Lancet, Volume 394, Issue 10215Author(s): Annelies Wilder-Smith, Stefan Flasche, Peter G Smith
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 12 December 2019Source: The LancetAuthor(s): Christopher C Butler, Alike W van der Velden, Emily Bongard, Benjamin R Saville, Jane Holmes, Samuel Coenen, Johanna Cook, Nick A Francis, Roger J Lewis, Maciek Godycki-Cwirko, Carl Llor, SÅ‚awomir Chlabicz, Christos Lionis, Bohumil Seifert, Pär-Daniel Sundvall, Annelies Colliers, Rune Aabenhus, Lars Bjerrum, Nicolay Jonassen Harbin, Morten LindbækSummaryBackgroundAntivirals are infrequently prescribed in European primary care for influenza-like illness, mostly because of perceived ineffectiveness in real world primary care and becau...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 12 December 2019Source: The LancetAuthor(s): Nelson Lee, Michael Ison
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionThe present study reports a variant subgroup GII-a PEDV HM2017 strain in China and characterize its pathogenicity. PEDV strain HM2017 of subgroup GII-a presents a promising vaccine candidate for the control of PED outbreaks in China.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
In this study H. pylori CagL gene was cloned in pAMJ2008 vector and transferred to Lactococcus lactis MG1363 as the host for CagL antigen production. This recombinant bacterium was orally subjected to mice, and the immune response to CagL was evaluated by ELISA. Intracellular expression of CagL protein was confirmed by Western blot analysis. Mucosal immunization of mice with the recombinant L. lactis significantly stimulated CagL-Specific antibodies: IgA, IgG, cytokine IL-17 and IN-γ. Moreover, the specific anti-CagL IgA response was detected in the feces of immunized mice. These results indicate that CagL of H. pylo...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 12 December 2019Source: Journal of Hospital InfectionAuthor(s): D.G. Wootton, S.J. Aston, T.W. Felton
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
ConclusionsThis study provides initial perspectives on measles preparedness among Idaho CAHs, despite limited generalizability. Future studies should explore whether self-reported preparedness measures reflect the ability of the CAHs to control measles spread when cases present for care.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
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