Association of Migraine Disorders Research Grant

Association of Migraine Disorders Research Grant The purpose of this RFP is to support novel and transformative evidence-based research into migraine-related disorders. A preference will be given to basic science projects. Specifically the purpose of this RFP is: 1. To understand the pathophysiology of the neural malfunction that is called migraine disease 2. To prove or disprove a common pathophysiology among the multiple symptoms and syndromes that claim a relationship to migraine 3. To improve our understanding of the natural history of migraine disease at various stages of life, such as the differences between episodic and persistent migraine symptoms 4. To describe the effects of hormones on migraine 5. To explore the genetic defects of migraine 6. To develop new diagnostic strategies to treat migraine 7. To improve the use of existing pharmaceutical agents and other treatments 8. To establish new pharmaceuticals or other treatments of migraine ELIGIBILITY Applicants must have demonstrated potential for excellence in research and teaching and a serious commitment to an academic research career in otolaryngology-head and neck surgery. A single principal investigator (PI) must be named. The position of “co-PI” is not acceptable. The PI should be associated with an academic institution. There are no restrictions on country of residence. All candidates must be sponsored by the Chairperson of his/her Division or Department. Applications ...
Source: ScanGrants feed - Category: Research Authors: Source Type: funding

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We present two cases of sphenoid sinus mucocele where patient presented with ophthalmoplegia, ptosis and/or sudden onset vision loss. With the help of imaging studies like CT scan and MRI of paranasal sinus diagnosis was made and immediate surgical intervention was planned which resulted in acceptable improvement of symptoms and vision.
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research
A 48-year-old male presented with worsening gait instability, blurry vision, headache, and intermittent emesis over a 4-month period. Magnetic resonance imaging of the brain demonstrated a right ventricular mass at the foramen of Monro with associated obstructive hydrocephalus (Fig 1). The lesion was well circumscribed and nonenhancing and measured 1.9 cm × 1.9 cm × 2.1 cm with minimal surrounding edema. A computed tomography scan of the chest/abdomen/pelvis showed no evidence of extracranial disease.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
Low-dose botox injections for jaw and facial pain not linked to bone changes, but NYU Dentistry researchers observe reduced bone density at higher dosesNew York UniversityBotox injections to manage jaw and facial pain do not result in clinically significant changes in jaw bone when used short term and in low doses, according to researchers at NYU College of Dentistry. However, they found evidence of bone loss when higher doses were used.The researchers, whose findings are published in theJournal of Oral Health Rehabilitation, call for further clinical studies to track bone- and muscle-related changes with long-term use of ...
Source: Dental Technology Blog - Category: Dentistry Source Type: news
AbstractHyperprolactinemia can have different causes: physiological, pharmacological, and pathological. When investigating the etiology of hyperprolactinemia, clinicians need to be aware of several conditions leading to misdiagnosis. The most popular pitfalls are: acute physical and psychological stress, macroprolactin, hook effect, even though antibodies interferences and biotine use have to be considered. A 52-year-old woman was referred to Endocrinology clinic for oligomenorrhoea and headache. She worked as a butcher. Hormonal evaluation showed very high PRL (305  ng/ml, reference interval:
Source: Endocrine - Category: Endocrinology Source Type: research
J Neurol Surg B Skull Base DOI: 10.1055/s-0040-1705158Ependymoma is one of the most common pediatric tumors in central nervous system, for which gross total resection has been the most favorable prognostic factor.1 2 However, surgery of ependymomas located in brain stem is significantly challenging. This video demonstrates the microsurgical removal of an ependymoma originating from ependymal cells of the lateral recess of fourth ventricle via retrosigmoid approach in an 11-year-old female. The patient presented with a 6-month history of continues headache and vomiting. On examination, she had a walking instability and a...
Source: Journal of Neurological Surgery Part B: Skull Base - Category: Neurosurgery Authors: Tags: Skull Base: Operative Videos Source Type: research
In this issue of the Journal of Stroke and Cerebrovascular Diseases, Chakraborty and colleagues describe the cautionary tale of a patient who presented with a thunderclap headache concerning for a subarachnoid hemorrhage (SAH). A head computed tomographic scan (CT) done 4  h after the onset of the headache was interpreted as negative but the patient was ultimately found to have an aneurysmal SAH.1
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
We report a recurrent case of frontal SPOA who had a previous history of craniotomy due to head trauma. The patient was presented with headache, facial swelling and diagnosed as frontal, ethmoid, and maxillary sinusitis with frontal SPOA, which is PPT. The patient was surgically managed by endoscopic sinus surgery and external drainage of the abscess. Although the symptoms had been relieved soon after the surgery, they were recurred after 1 week. By paranasal sinus computed tomography scans, it was suspected that severe carious teeth, which were missed before surgery, induced maxillary sinusitis which spread into the front...
Source: Ear, Nose and Throat Journal - Category: ENT & OMF Authors: Tags: Ear Nose Throat J Source Type: research
n A Abstract OBJECTIVE: To analyze the relationship between different sites of elicited pain to muscle palpation (PtP), and reported frequent pain in jaw-face and head. MATERIALS AND METHODS: The analysis was based on an epidemiological sample of 1200 randomly selected individuals, of which 779 (65%) both completed a questionnaire and participated in a clinical examination. The questionnaire addressed the presence of pain in the jaw-face region and headache, respectively. Part of the clinical examination entailed palpation of the jaw, neck, shoulder, arm, thumb and calf muscles. Logistic regression was applie...
Source: Acta Odontologica Scandinavica - Category: Dentistry Authors: Tags: Acta Odontol Scand Source Type: research
This study aims to examine the effectiveness of levoamlodipine maleate used to treat outpatients with primary hypertension compared with amlodipine besylate in a real-world setting.MethodsThis was a pragmatic comparative effectiveness study carried out at 110 centers across China in outpatients with primary hypertension treated with levoamlodipine maleate or amlodipine besylate, with 24  months of follow-up. The primary outcomes used for evaluating the effectiveness were composite major cardiovascular and cerebrovascular events (MACCE), adverse reactions, and cost-effectiveness.ResultsAmong the included 10,031 patient...
Source: Cardiovascular Drugs and Therapy - Category: Cardiology Source Type: research
ConclusionThere was no significant correlation regarding aberrations of lead position from the planned position with clinical outcome. However, this study might be underpowered to detect such a correlation. The closest electrode contact to the vidian canal was in the stimulation area in all but one patient in the final programming. This indicates that, overall, the lead location does play a crucial role in SPG stimulation for cluster headache.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
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