Cardiovascular comorbidities in a United States patient population with hemophilia A: A comprehensive chart review.

Cardiovascular comorbidities in a United States patient population with hemophilia A: A comprehensive chart review. Adv Med Sci. 2018 Jul 18;63(2):329-333 Authors: Humphries TJ, Rule B, Ogbonnaya A, Eaddy M, Lunacsek O, Lamerato L, Pocoski J Abstract PURPOSE: Previous retrospective claims database analyses reported increased prevalence and earlier onset of cardiovascular comorbidities in patients with versus without hemophilia A. A comprehensive chart review was designed to further investigate previous findings. METHODS: This retrospective chart review study was conducted at Henry Ford Health System (Detroit, MI, USA). Baseline demographics, bleeding events, treatment parameters, coexisting diseases, hemophilia-associated events, Charlson Comorbidity Index score, and prevalence of 12 cardiovascular risk factors and associated diseases were compared between hemophilia A and control cohorts. P values from a chi-square test for categorical variables and a t test for continuous variables were calculated. Because of small sample sizes (N = 0-90, most
Source: Advances in Medical Sciences - Category: Biomedical Science Authors: Tags: Adv Med Sci Source Type: research

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