What Medicines Should Be Avoided with G6PD Deficiency?

Discussion Glucose 6-phosphate dehydrogenase deficiency (G6PD) is an X-linked disease that has multiple mutations. Each mutation causes a different amount of the enzyme to be produced within cells and therefore not all mutations will produce disease. Glucose 6-phosphate dehydrogenase is an enzyme that is critical to the metabolism of all aerobic cells as it catalyzes the rate-limiting step of the pentose phosphate pathway reducing NADP to NADPH. NADPH is important for nucleic acid replication and therefore cell division. G6PD is the only source of NADPH within the cell, so deficiency makes red blood cells susceptible to hemolysis if they are under oxidative stress. Populations at higher risk for G6PD include those who their ethnic heritage is from the Mediterranean, Africa, Middle East and Asia. Newborn screening testing is not routinely done in the United States. Infants are often identified because of the early timing, persistent or extreme levels of hyperbilirubinemia. Although the levels of hyperbilirubinemia in this patient were not extreme (i.e.> 20 mg/dL), G6PD is a common reason for extreme hyperbilirubinemia. Causes of severe unconjungated hyperbilirubinemia specifically due to problems with red blood cells can be found here. A review of general causes of neonatal unconjugated hyperbilirubinemia can be found here. Learning Point Hemolytic episodes in persons with G6PD can be triggered by infections, severe stress, certain foods (such as fava beans), and certain ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

Related Links:

This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Petra Juskova, Steven Schmitt, Lucas Armbrecht, Petra S Dittrich Microbial cells represent a standard production host for various important biotechnological products. Production yields can be increased by optimising strains, growth conditions and understanding deviations in production rates over time... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Lab Chip latest articles - Category: Chemistry Authors: Source Type: research
VITAMINS can give you the energy boost you need to live life to the fullest. If you're feeling a bit run down, you might need to look into supplements for these vitamins.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The vitamin helps to enhance the immune response to the virus.
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: COVID19 Source Type: blogs
Diseases linked to vitamin D deficiency include cardiovascular disease, diabetes and cancer.
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Nutrition Source Type: blogs
Trends Parasitol. 2021 Sep 21:S1471-4922(21)00224-5. doi: 10.1016/j.pt.2021.08.011. Online ahead of print.ABSTRACTIn the early 2000s, artemisinin-based combination therapy (ACT) was introduced as first-line treatment for uncomplicated Plasmodium falciparum malaria in virtually all endemic countries. However, despite the well-known excellent tolerability of ACTs, hypersensitivity to artemisinin derivatives remains a repeatedly documented adverse drug reaction of still unknown frequency. The clinical features of an artemisinin-induced hypersensitivity reaction range from mild to life-threatening severity, and a significant n...
Source: Trends in Parasitology - Category: Parasitology Authors: Source Type: research
This article was originally published by OpenGlobalRights
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Economy & Trade Global Global Governance Headlines Health Human Rights TerraViva United Nations Source Type: news
Condition:   To Establish Bioequivalence of a Novel Formulation PL-ASA to Immediate Release Aspirin Intervention:   Drug: Pharmaceutical-lipid aspirin (PL-ASA) Sponsor:   PLx Pharma Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   AMD;   Soft Drusen;   Reticular Pseudodrusen;   Drusen Stage Macular Degeneration;   Drusen (Degenerative) of Macula, Bilateral Interventions:   Dietary Supplement: Postbotics and Vitamins;   Dietary Supplement: Vitamins Sponsors:   Institut de la Macula y la Retina;   Igen BioLab SLU Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   To Establish Bioequivalence of a Novel Formulation PL-ASA to Immediate Release Aspirin Intervention:   Drug: Pharmaceutical-lipid aspirin (PL-ASA) Sponsor:   PLx Pharma Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   AMD;   Soft Drusen;   Reticular Pseudodrusen;   Drusen Stage Macular Degeneration;   Drusen (Degenerative) of Macula, Bilateral Interventions:   Dietary Supplement: Postbotics and Vitamins;   Dietary Supplement: Vitamins Sponsors:   Institut de la Macula y la Retina;   Igen BioLab SLU Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Acetaminophen | Aczone Gel | African Health | Aspirin | Bilirubin | Broad Beans | Children | Databases & Libraries | G6PD | Genetics | Health | Health Management | Hematology | Hospital Management | Hospitals | Jaundice | Laboratory Medicine | Learning | Lortab | Malaria | Middle East Health | Nitrofurantoin | Papanicolaou (Pap) Smear | Pediatrics | Perinatology & Neonatology | Phenazopyridine | Universities & Medical Training | Vitamin K Deficiency | Vitamins