Late-Breaking Phase 3 A DUE Data Show Investigational Single Tablet Combination Therapy of Macitentan and Tadalafil Significantly Improves Pulmonary Hemodynamics versus Monotherapy in Patients with Pulmonary Arterial Hypertension (PAH)
RARITAN, NJ, March 6, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced results from the Phase 3 A DUE study (NCT03904693), which showed an investigational once-daily, single tablet combination therapy, also known as fixed dose combination, of macitentan 10 mg and tadalafil 40 mg (M/T STCT), significantly improved pulmonary hemodynamics (blood flow through pulmonary blood vessels) versus macitentan and tadalafil monotherapies in pulmonary arterial hypertension (PAH) patients with World Health Organization (WHO) functional class (FC) II or III.[1] The data were presented today as a Late-...
Source: Johnson and Johnson - March 6, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Mayo Clinic Q and A: What is cholangiocarcinoma and how is it treated?
DEAR MAYO CLINIC: My mother has been experiencing unusual and persistent fatigue, abdominal pain, and jaundice. After undergoing a CT scan, her doctor diagnosed her with cholangiocarcinoma. What is this type of cancer? And what treatment options are available? ANSWER: Cholangiocarcinoma is a rare cancer that develops from the bile ducts, which are slender tubes that carry the digestive fluid bile and connect the liver to the gallbladder and small intestine. The tumor can occur anywhere along… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 21, 2023 Category: Databases & Libraries Source Type: news
Singapore ’s deep-tech start-ups help to change the world
Innovation helps E3A Healthcare cut cost of key jaundice monitoring device component by over 100 times while Wasna creates low-cost, animal-free growth serum to cultivate affordable meat#healthcare (Source: Reuters: Health)
Source: Reuters: Health - January 19, 2023 Category: Consumer Health News Source Type: news
Smartphone-Based Scleral Imaging Can ID Jaundice in Decompensated Cirrhosis
WEDNESDAY, Jan. 11, 2023 -- Smartphone-based assessment of jaundice in patients with decompensated cirrhosis is feasible and accurate, mirroring levels of bilirubin and its correlations with clinical parameters, according to a study published online... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 11, 2023 Category: Pharmaceuticals Source Type: news
'There's no cure': Jaundice in your skin can signal irreversible fatty liver disease
Paying attention to any changes in your skin could mean the difference between spotting cirrhosis and letting it slide. (Source: Daily Express - Health)
Source: Daily Express - Health - December 29, 2022 Category: Consumer Health News Source Type: news
Thallium poisoning: a case report - Jimenez O, C áceres H, Gimenez L, Soto L, Montenegro M, Rueda JAA.
We present a case of a 51-year-old woman who was evaluated in June 2018 for myalgia, vertigo, asthenia, and abdominal pain. Physical examination revealed temporal-spatial disorientation, jaundice, and asterixis. Th... (Source: SafetyLit)
Source: SafetyLit - December 26, 2022 Category: International Medicine & Public Health Tags: Poisoning Source Type: news
Man, 63, diagnosed with pancreatic cancer after experiencing 'very bad' itching & jaundice
The man's experience highlights the need to get any unusual changes checked by your GP. (Source: Daily Express - Health)
Source: Daily Express - Health - December 18, 2022 Category: Consumer Health News Source Type: news
Jaundice in a 10-hour-old Infant
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - December 1, 2022 Category: Pediatrics Source Type: news
Spinal cord of boy, 13, ‘seriously damaged’ due to severe B12 deficiency - signs to spot
He experienced memory problems, "extreme" fatigue, jaundice and lost the ability to walk or write as a result of his deficiency. (Source: Daily Express - Health)
Source: Daily Express - Health - November 21, 2022 Category: Consumer Health News Source Type: news
Which Side Are the Organs On?
Discussion
Although externally vertebrates present with bilateral symmetry, this is not necessarily true internally for humans. Humans have a normal left-right asymmetry of their internal organs. For example, the right lung has 3 lobes and is slightly larger than the left lung with 2 lobes. The normal asymmetry is called situs solitus (SS). Complete reversal of the normal abdominal and thoracic organ positions is called situs inversus totalis (SIT). Variations on the laterality between situs solitus and SIT has been referred to by different names including situs ambiguous or heterotaxy. For this case, the term situs ambigu...
Source: PediatricEducation.org - October 17, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
October 2022
Kids ’ Sleep Linked to Brain Health
How Many Is Too Many? : When Drinking Becomes a Problem
Recognizing Jaundice : Signs That Your Liver Isn ’t Delivering
Vaccinations and Older Adults
Adult Hearing Health Care (Source: NIH News in Health)
Source: NIH News in Health - September 27, 2022 Category: Consumer Health News Source Type: news
How Long Does A Cephalohematoma Take to Resolve?
Discussion
Cephalomatomas occur relatively commonly in 0.2-3% of newborn infants. They are blood collections in the subperiosteal skull bones, usually in the parietal area. They are usually unilateral but can be bilateral. They do not transilluminate. They are felt to be caused by pressure or other trauma and occur in vaginal and cesarean deliveries, with presumed periosteal disruption leading to externally located bleeding (not on the brain side of the bone). The blood fills the space with some pressure building up and the blood acts to tamponade itself. The blood coagulates, slowly organizes and is reabsorbed. If reabsor...
Source: PediatricEducation.org - September 12, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
South Africa: In-Depth - the Human Cost of Surgical Delays
[spotlight] It is the fifth week of her husband waiting on a surgical procedure for a stent at Tygerberg Hospital when Spotlight catches up with *Mrs Brooks. In February this year, they saw a GP where they live who diagnosed him with jaundice. Tests showed that there was a mass growing on the pancreas that is closing the gallbladder pipe (bile duct) and obstructing bile. By then, Mrs Brooks says, her husband had already lost 12 kg. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 20, 2022 Category: African Health Source Type: news
Jaundice, Malaise in Woman With Heroin Habit, Inactive Hepatitis B
(MedPage Today) -- HDV diagnosis portends imminent cirrhosis despite initial resolution of symptoms (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - July 5, 2022 Category: Gastroenterology Source Type: news
Machine-learning algorithms can help health care staff correctly diagnose alcohol-associated hepatitis, acute cholangitis
ROCHESTER, Minn. — Acute cholangitis is a potentially life-threatening bacterial infection that often is associated with gallstones. Symptoms include fever, jaundice, right upper quadrant pain, and elevated liver enzymes. While these may seem like distinctive, telltale symptoms, unfortunately, they are similar to those of a much different condition: alcohol-associated hepatitis. This challenges emergency department staff and other health care professionals who need to diagnose and treat patients with liver enzyme abnormalities and systemic inflammatory responses.… (Source: Mayo Clinic Arizona News)
Source: Mayo Clinic Arizona News - July 1, 2022 Category: Hospital Management Source Type: news
