Oral Antibiotic Exposure and Kidney Stone Disease
This research article found exposure to any of following 5 antibiotics 3 –12 months before index date was linked to nephrolithiasis (sulfas, cephalosporins, fluoroquinolones, nitrofurantoin/methenamine, and broad-spectrum penicillins; ORs from 1.27 to 2.33). (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 22, 2018 Category: Consumer Health News Source Type: news

Here ’s Another Reason to Avoid Taking Unnecessary Antibiotics
Taking certain oral antibiotics may come with an unpleasant side effect, according to new research. A study published Thursday in the Journal of the American Society of Nephrology found that taking any of five types of oral antibiotics was associated with a significantly higher risk of developing kidney stones — mineral and salt deposits that form in the kidneys and must be passed through the urinary tract. Kidney stones have grown much more common over the past few decades without a clear explanation as to why. The condition is, however, associated with bacterial changes in the intestines and urinary tract, leading ...
Source: TIME: Health - May 12, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime medicine onetime Source Type: news

Antibiotics Tied to Higher Kidney Stone Risk
The five antibiotic classes newly linked to kidney stone risk included sulfas (Bactrim, Gantanol); cephalosporins (Keflex); fluoroquinolones (Cipro); nitrofurantoin/methenamine (Macrobid, Hiprex); and broad-spectrum penicillins. (Source: WebMD Health)
Source: WebMD Health - May 11, 2018 Category: Consumer Health News Source Type: news

Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women
This research article concludes that clinical resolution to day 28 (primary endpoint) was achieved in more women with uncomplicated urinary tract infection, treated with 5-day nitrofurantoin vs single dose fosfomycin. Microbiological cure was also more favourable. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 2, 2018 Category: Consumer Health News Source Type: news

Five-Day Nitrofurantoin Beats Single-Dose Fosfomycin for UTI
TUESDAY, April 24, 2018 -- Five-day nitrofurantoin is associated with increased likelihood of clinical and microbiological resolution compared with single-dose fosfomycin among women with lower urinary tract infection (UTI), according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 24, 2018 Category: Pharmaceuticals Source Type: news

Pregnant Women Getting UTI Meds Linked to Defects
The antibiotics -- trimethoprim-sulfamethoxazole (Bactrim) and nitrofurantoin (Macrobid) -- have been linked to a small risk for birth defects in pregnant women when given in the first trimester. (Source: WebMD Health)
Source: WebMD Health - January 12, 2018 Category: Consumer Health News Source Type: news

Cadila gets USFDA nod for generic drug to treat Parkinson's
The Ahmedabad-based firm also received final approval from the USFDA to market Nitrofurantoin Capsules USP, used for treating acute uncomplicated urinary tract infections, in the US market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 14, 2017 Category: Pharmaceuticals Source Type: news

Macrobid (Nitrofurantoin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 14, 2017 Category: Drugs & Pharmacology Source Type: news

Furadantin (Nitrofurantoin Oral Suspension) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 26, 2016 Category: Drugs & Pharmacology Source Type: news

2,839 bottles of Sun Pharma Inc being recalled in US
The ongoing nationwide voluntary recall by Nostrum Laboratories Inc for Nitrofurantoin Oral Suspension, USP, 25 mg/5 mL is a class II recall, report said. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - June 22, 2016 Category: Pharmaceuticals Source Type: news

Common antibiotic for children 'ineffective in half of cases'
Conclusion This is an important study that may mean doctors need to change the way they treat one of the most common childhood illnesses. Because urine infections can be painful and can damage the kidneys in young children, it's important they are treated quickly and effectively. Current guidelines for doctors, which were published nine years ago, say children over three months of age with urine infections should be treated for three days with an antibiotic "directed by locally developed guidance", which might include trimethoprim, nitrofurantoin, cephalosporin or amoxicillin. Only if the antibiotic does not w...
Source: NHS News Feed - March 16, 2016 Category: Consumer Health News Tags: Medication Pregnancy/child Source Type: news

Antibiotic Treatment Strategies for UTI
The selection of antibiotics for urinary tract infection (UTI) in long-term care is an evolving area, with nitrofurantoin receiving increased attention and experts' increased encouragement for the use of antibiograms to assist with drug choice. (Source: Caring for the Ages)
Source: Caring for the Ages - August 1, 2015 Category: Health Management Source Type: news

Study Casts Doubt on Use of Common Antibiotic for UTIs in Women
Canadian researchers find other antibiotics may beat nitrofurantoin, but one expert says drug still useful Source: HealthDay Related MedlinePlus Pages: Antibiotics, Urinary Tract Infections, Women's Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - April 30, 2015 Category: Consumer Health News Source Type: news

Antibiotic Commonly Used for UTI Less Effective Than OthersAntibiotic Commonly Used for UTI Less Effective Than Others
Nitrofurantoin is less effective for treatment of urinary tract infections in older women than other first-line antibiotics. Renal function did not appear to affect treatment failure. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 28, 2015 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Nitrofurantoin's Antibiotic Action Further ExploredNitrofurantoin's Antibiotic Action Further Explored
In vitro pharmacodynamic studies of nitrofurantoin, an antibiotic used to treat urinary tract infections (UTI) since the 1960s, are shedding new light on the agent's action, Swedish investigators say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 31, 2014 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

nitrofurantoin, Macrodantin, Furadantin, Macrobid
Title: nitrofurantoin, Macrodantin, Furadantin, MacrobidCategory: MedicationsCreated: 3/26/1998 12:00:00 AMLast Editorial Review: 10/22/2014 12:00:00 AM (Source: MedicineNet Hepatitis C General)
Source: MedicineNet Hepatitis C General - October 22, 2014 Category: Infectious Diseases Source Type: news

What Medicines Should Be Avoided with G6PD Deficiency?
Discussion Glucose 6-phosphate dehydrogenase deficiency (G6PD) is an X-linked disease that has multiple mutations. Each mutation causes a different amount of the enzyme to be produced within cells and therefore not all mutations will produce disease. Glucose 6-phosphate dehydrogenase is an enzyme that is critical to the metabolism of all aerobic cells as it catalyzes the rate-limiting step of the pentose phosphate pathway reducing NADP to NADPH. NADPH is important for nucleic acid replication and therefore cell division. G6PD is the only source of NADPH within the cell, so deficiency makes red blood cells susceptible to he...
Source: PediatricEducation.org - September 15, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Steep rise in antibiotic use for coughs and colds
ConclusionThis cross-sectional study has found the proportion of people with coughs and colds that are prescribed antibiotics rose from 36% in 1999 to 51% in 2011 – an increase of approximately 40%. This is despite the publication of guidance recommending that GPs do not prescribe antibiotics for coughs and colds. It also found substantial variation between different GP practices, with 10% of practices prescribing antibiotics for less than 32% of cases and 10% of practices prescribing antibiotics for more than 65% of cases, suggesting that substantially lower rates of prescribing could be achieved.The ...
Source: NHS News Feed - August 5, 2014 Category: Consumer Health News Tags: Medical practice Medication Source Type: news

Why Should Nitrofurantoin Be Avoided in the Elderly?Why Should Nitrofurantoin Be Avoided in the Elderly?
What is the reason for not using nitrofurantoin in older patients? Medscape Pharmacists (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 10, 2013 Category: Consumer Health News Tags: Family Medicine/Primary Care Ask the Expert Source Type: news

Observational study suggests nitrofurantoins may pose little risk of birth defects
Source: Obstetrics and Gynecology, Reuters Health Area: News A large observational study in Norway, published in the February edition of the journal of Obstetrics and Gynaecology, suggests that nitrofurantoins may pose little risk for birth defects when taken during pregnancy.   The researchers studied a Norwegian national birth registry and a national prescription database for pregnancies in 2004-2008 to find 5,794 women exposed to nitrofurantoins (3.2%) at different stages during their pregnancy, (1,334 women (0.7%) in the first trimester and 979 women (0.5%) in the last 4 weeks of pregnancy). They compared the...
Source: NeLM - News - February 1, 2013 Category: Drugs & Pharmacology Source Type: news