The potential effect of garlic extract and curcumin nanoparticles against complication accompanied with experimentally induced diabetes in rats

Conclusion Nano-Curcumin and AGE suspension have a great therapeutic potential in the treatment of DCM, Diabetic cardiomyopathy, by attenuating cardiac inflammation, myocardial fibrosis, and programmed myocardial cell deaths through inhibiting OS and AGEPs accumulation in diabetic heart tissue. Furthermore, the hypoglycemic antioxidant properties of AGE resulted in more potent therapeutic effect than Nano-Curcumin in the treatment of diabetic hearts. Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research