Request for Applications: Center for Orphan Disease Research and Therapy Postdoctoral Fellowship for Research Related to Congenital Muscular Dystrophy

Request for Applications: Center for Orphan Disease Research and Therapy Postdoctoral Fellowship for Research Related to Congenital Muscular Dystrophy The CODRT Postdoctoral Fellowship provides a one‐year grant of $35,000 to support the salary of a Fellow while working on a mentored project related to a CODRT-funded disease. Eligibility At the time of application, the applicant must possess a Ph.D., M.D., or V.M.D. and should not have completed more than 5 years of postdoctoral research. At the time of award, the applicant must not be simultaneously serving an internship or residency. Applicants must work for a non-profit institution or foundation, and may not have a faculty appointment. There are no citizenship requirements for this program. Overview of Science: Congenital Muscular Dystrophy (CMD) are a group of genetically inherited multi-system disorder with symptom onset at birth and progressive muscle weakness, respiratory insufficiency, contractures and scoliosis. Failure to thrive, cardiac arrhythmias, subclinical cardiomyopathy and seizures may complicate disease course. The purpose of this RFA is to evaluate underlying disease mechanisms that might prove to be targetable by drugs or an intervention. The funding will be used to generate preliminary data of sufficient quality to evaluate the plausibility of additional preclinical testing. The timeline for the RFA/grant program is as follows: Time Lines: RFA Release Posted: August 1, 2014 Pre-applica...
Source: ScanGrants feed - Category: Research Authors: Source Type: funding

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Source: Journal of Toxicology and Environmental Health Part A - Category: Environmental Health Authors: Source Type: research
Authors: Bergland OU, Søraas CL, Larstorp ACK, Halvorsen LV, Hjørnholm U, Hoffman P, Høieggen A, Fadl Elmula FEM Abstract PURPOSE: The blood pressure (BP) lowering effect of renal sympathetic denervation (RDN) in treatment-resistant hypertension shows variation amongst the existing randomised studies. The long-term efficacy and safety of RDN require further investigation. For the first time, we report BP changes and safety up to 7 years after RDN, compared to drug adjustment in the randomised Oslo RDN study. MATERIALS AND METHODS: Patients with treatment-resistant hypertension, defined...
Source: Blood Pressure - Category: Hematology Tags: Blood Press Source Type: research
CONCLUSIONS: Immunohistochemistry seems to be a promising option not only in clinical recognition, but also in the selection and monitoring of treatment effects. However, these methods have not yet recommended for routine clinical use. PMID: 33032462 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
CONCLUSIONS: Neuro-ophthalmologic findings are mostly normal in patients with visual snow syndrome. Retinal or neurological diseases must be excluded as possible causes of visual snow. PMID: 33029971 [PubMed]
Source: Journal of Clinical Neurology - Category: Neurology Tags: J Clin Neurol Source Type: research
CONCLUSIONS: Paramagnetic rims might be a characteristic MRI finding for MS, and therefore they have potential as an imaging marker for differentially diagnosing MS from NMOSD using 3-T MRI. PMID: 33029961 [PubMed]
Source: Journal of Clinical Neurology - Category: Neurology Tags: J Clin Neurol Source Type: research
CONCLUSION: When gastroenterologists encounter NAFLD/NASH patients, serum CK should be verified. If hyperCKemia, frontal baldness, a hatched face, history of cataract surgery, and grip myotonia are noted, the possibility of MD may be considered. PMID: 33033573 [PubMed]
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
Publication date: Available online 9 October 2020Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Hande Gurbuz Aytuluk, Kemal Tolga Saracoglu
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
Authors: Tsujioka S, Nozoe M, Kawano Y, Suematsu N, Kubota T Abstract A 70-year-old woman with situs inversus totalis underwent catheter ablation for atrial fibrillation and atrial flutter. Although her morphologic left atrium (LA) was enlarged, we performed cryoballoon ablation and liner radiofrequency ablation of the cava-tricuspid isthmus without mapping atrial arrhythmias. However, a different form of atrial tachycardia (AT) recurred. We performed catheter ablation a second time using a three-dimensional electroanatomic mapping system. AT was not terminated by the liner ablation at the roof of morphologic LA an...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
From 5G to a fancy scanner
Source: Reuters: Health - Category: Consumer Health News Source Type: news
The vestibulo-ocular reflex (VOR) is a dynamic system of the human brain that helps to maintain balance and to stabilize vision during head movement. The video head impulse test (vHIT) is a clinical test that uses lightweight, high-speed video goggles to e...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
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