Strong antitumor efficacy of a pancreatic tumor ‐targeting oncolytic adenovirus for neuroendocrine tumors

In this study, we found that this adenovirus showed an even higher gene transduction efficiency and oncolytic potency for pancreatic neuroendocrine tumors in vitro, in a mouse model, and using clinical specimens of various human cancers. The data suggest that the virus, AdSur‐SYE, is a promising next‐generation therapy agent for pancreatic neuroendocrine tumors.

Source: Cancer Medicine - September 21, 2017 Category: Cancer & Oncology Authors: Yuki Yamamoto, Masaki Nagasato, Yosei Rin, Marina Henmi, Yoshinori Ino, Shinichi Yachida, Rieko Ohki, Nobuyoshi Hiraoka, Masatoshi Tagawa, Kazunori Aoki Tags: Original Research Source Type: research