Log in to search using one of your social media accounts:

 

Age at menopause and hormone replacement therapy as risk factors for head and neck and oesophageal cancer  (Review).

Age at menopause and hormone replacement therapy as risk factors for head and neck and oesophageal cancer (Review). Oncol Rep. 2017 Aug 01;: Authors: McCarthy CE, Field JK, Marcus MW Abstract There were ~986,000 cases of head and neck cancer (HNC) and oesophageal cancer diagnosed worldwide in 2012. The incidence of these types of cancer is much higher in males than females, although this disparity decreases in the elderly population, suggesting a role for hormones as a risk factor. This systematic review investigates the potential role of female hormones [age at menopause and use of hormone replacement therapy (HRT)] as risk factors for HNC/oesophageal squamous cell carcinoma (SCC). The electronic databases MEDLINE, Web of Science, EMBASE and Cochrane were searched. Only studies with at least 50 cases of HNC/oesophageal SCC, with data on age at menopause, smoking, alcohol, age and socioeconomic status or educational attainment, were included. The Newcastle Ottawa Scale was used for assessing risk of bias. Eight studies met the inclusion criteria (5 oesophageal SCC, 2 HNC and 1 combined oesophageal SCC and HNC). HRT was shown to reduce the risk of HNC (HR, 0.78; 95% CI, 0.61-0.99) in one study. Our results showed that earlier age at menopause is a risk factor for oesophageal SCC, with women entering menopause at 50 years. Similar, but less striking, results were observed for HNC. HRT was found to reduce the...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research

Related Links:

(MedPage Today) -- Peter Ubel, MD, explains how to let older patients know tests won't help
Source: MedPage Today Hematology/Oncology - Category: Hematology Source Type: news
A preplanned analysis of ctDNA found that a subpopulation of mCRC patients with acquired anti-EGFR resistance were sensitive to treatment with Sym004.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Tags: Colorectal Cancer Immuno Oncology News Source Type: news
The addition of metronomic chemotherapy to dual HER2 blockade improved outcomes in older and frail patients with HER2-positive metastatic breast cancer.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Tags: Breast Cancer HER2-Positive Breast Cancer News Source Type: news
Date: Wednesday, 03 21, 2018; Speaker: Charles Rabkin, M.D., Senior Investigator, Division of Cancer Epidemiology and Genetics, NCI; https://epi.grants.cancer.gov/events
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Thursday, 03 29, 2018; Speaker: Cassandra Harris, M.S., M.C.H.E.S., Manager, Health Education, MD Anderson Cancer Center; Kathi Ridley-Merriweather, M.A., Communications and Minority Outreach Coordinator, Komen Tissue Bank; Ren é Arnold, M.B.A., Former Operations Manager, The Fountain of Praise Church; https://epi.grants.cancer.gov/events/enrich-forum/
Source: NIH Calendar of Events - Category: American Health Source Type: events
CUTTING down on how much we drink could slash the risk of dementia by a third. Scientists say heavy boozing is a “major factor” in all forms of the incurable illness, having looked at 57,000 cases of dementia diagnosed before 65.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The Wayne D. Kuni&Joan E. Kuni Foundation has awarded $5 million to Legacy Health Foundation to found a cancer research project. The grant will fund research into how cancer can be targeted by manipulating adenosine kinase, an enzyme that controls cell growth. The research is led by Detlev Boison, Dow Chair of Neurology and director of neurobiology research and basic and translational research at Legacy Research Institute; and Dr. Serene Perkins, director of surgical and clinical research at…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
Cabozantinib showed significant antitumor activity in the treatment of differentiated thyroid cancer that progressed following surgery and radioactive iodine therapy, according to a new phase II study.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Tags: News Thyroid Cancer Source Type: news
An early phase trial found that it is feasible to combine nivolumab immunotherapy with radiation therapy and chemotherapy in patients with newly diagnosed local-regionally advanced head and neck cancers.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Tags: Head & Neck Cancer News Radiation Oncology Source Type: news
Oncologists need to play a larger role in discussing exercise with cancer survivors, and home-based exercise interventions offer advantages, say Australian researchers.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
More News: Alcoholism | Cancer | Cancer & Oncology | Carcinoma | Databases & Libraries | Education | Epidemiology | Esophagus Cancer | Head and Neck Cancer | Hormone Replacement Therapy | Hormones | Laboratory Medicine | Men | Menopause | Science | Skin Cancer | Smokers | Squamous Cell Carcinoma | Study | Women