Nrf2 Is Crucial For The Down-Regulation Of Cyp7a1 Induced By Arachidonic Acid In Hepg2 Cells

In conclusion, Nrf2 plays a significant role in the down-regulation of CYP7A1 induced by AA in HepG2 cells.Abbreviations: AA, arachidonic acid; CYP7A1, cholesterol 7α-hydroxylase; FA, fatty acid; HFD, high-fat diet; NAFLD, non-alcoholic fatty liver disease; Nrf2, nuclear factor erythroid-derived 2-like 2; siRNA, small interfering RNA.
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research