Duke Clinical Research Institute to Coordinate National Study of Childhood Health

Contact: Sarah Avery Phone: 919-660-1306 Email:sarah.avery@duke.eduhttps://www.dukehealth.orgFOR IMMEDIATE RELEASE on Wednesday, Sept. 21, 2016DURHAM, N.C. -- TheDuke Clinical Research Institute (DCRI) has been named the coordinating center as part of a $157-million federal initiative involved in studying how environmental factors affect childhood health.The grant from the National Institutes of Health (NIH) will fund the organizational framework of the Environmental Influences on Child Health Outcomes (ECHO) initiative. The DCRI has been awarded $14.7 million in fiscal year 2016. This award is a seven-year grant with a total value of $119 million.As the coordinating center for the research initiative, the DCRI will provide support to the study ’s steering committee, lead site training for participating research teams, develop common rules and standard procedures, monitor quality controls, and establish and maintain websites and other communications tools.The ECHO coordinating center at DCRI will also include an Opportunities and Infrastructure Fund to support pilot projects, encourage development of junior investigators, and introduce new tools and technologies in the context of the ECHO program.  “We are certainly honored to be selected as the coordinating center for this important research initiative at the NIH,” said principal investigatorBrian Smith, M.D., a Duke neonatologist and faculty member of the DCRI. “This builds on a number of our st...
Source: DukeHealth.org: Duke Health Features - Category: Pediatrics Tags: Duke Medicine Source Type: news

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Background and Objective: Maternal obesity has been associated with asthma in the offspring. Our aim was to evaluate the trimester specific effect of gestational weight gain in asthmatic mothers on the risk of asthma in the offspring.Methods: Since 2007 all pregnant women referred to give birth at Hvidovre Hospital, DK, have been offered participation in the prospective Management of Asthma during Pregnancy (MAP) program. Women were included in the present analysis if they fulfilled the following criteria: 1) diagnosed with asthma, 2) prescribed at least rescue bronchodilator, 3) had the first outpatient visit at the Respi...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
ConclusionsThe benefits of FENO-based management are attenuated among obese mothers and those with excess GWG, indicating the importance of weight management in contributing to improved asthma management in pregnancy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
ConclusionsThe benefits of FENO -based management are attenuated among obese mothers and those with excess GWG, indicating the importance of weight management in contributing to improved asthma management in pregnancy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
ConclusionsPoorly controlled asthma is more frequent among publicly versus privately insured pregnancies in the United States. Dispensing of long-term controller medications during pregnancy remains low, even for symptomatic patients.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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Source: OnMedica Latest News - Category: UK Health Source Type: news
In a world of social companion robots, chatbots, or artificial intelligence buddies, adults have the responsibility to teach kids well how to live a healthy life with the available technologies, how to balance between the online and the offline world, how to keep their mental stability in the face of innovations. As it’s an awfully difficult job, we collected examples where digital health technology could help and in which areas should analog methods prevail. The land where kindergarteners play with the texture of raspberry When was the last time you paid attention to the crunching sounds while eating a raw ca...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Health Sensors & Trackers apps children cognitive health digital health digital literacy eating fitness health apps health literacy healthy eating healthy lifestyle Innovation kids mental health physical Source Type: blogs
Abstract The anti-inflammatory diet is based on two diets that have been shown to have many positive health effects-the Mediterranean diet and the Okinawan diet. The anti-inflammatory diet is more than just a prescription for healthy food, but rather a way of life characterized by a plant-based diet and a pattern of living that includes eating a diverse range of locally grown foods eaten in season, conviviality, culinary activities, physical activity, and rest. The Mediterranean diet has been shown to reduce the burden and even prevent the development of cardiovascular disease, breast cancer, depression, colorecta...
Source: Pediatric Annals - Category: Pediatrics Authors: Tags: Pediatr Ann Source Type: research
In the United States and other developed countries, we have seen a shift over the past several decades in the types of illness people struggle with. Public health campaigns around vaccination, sanitation, and judicious use of antibiotics have largely eradicated many infectious illnesses. As the nature of disease has shifted to inflammatory conditions, we’ve seen a striking increase in allergy and autoimmune conditions such as diabetes, obesity, inflammatory bowel disease, celiac disease, and multiple sclerosis. The microbiome — the varied and teeming colonies of gut bacteria inside of us — may be helping ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Family Planning and Pregnancy Inflammation Probiotics Source Type: blogs
Maunil K. Desai1 and Roberta Diaz Brinton2,3* 1School of Pharmacy, University of Southern California, Los Angeles, CA, United States 2Center for Innovation in Brain Science, University of Arizona, Tucson, AZ, United States 3Departments of Pharmacology and Neurology, College of Medicine, University of Arizona, Tucson, AZ, United States Women have a higher incidence and prevalence of autoimmune diseases than men, and 85% or more patients of multiple autoimmune diseases are female. Women undergo sweeping endocrinological changes at least twice during their lifetime, puberty and menopause, with many women undergoin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusions and Future Perspectives It is now evident that NK/ILC family plays a pivotal role in the immune defenses. Recent studies in murine and human settings demonstrated that the expression of several inhibitory checkpoints, that may be detrimental in the tumor context, is not restricted to T lymphocytes, revealing an important, yet poorly appreciated, contribution of their expression on innate immune cells. Thus, in the recent years different immunotherapy approaches, based on the blockade of inhibitory NK cell receptors, have been developed in order to unleash NK cell cytotoxicity. This is particularly important in...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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