Incidence and molecular characteristics of deficient mismatch repair conditions across nine different tumors and identification of germline variants involved in Lynch-like syndrome

CONCLUSIONS: Our data regarding the LS to LLS ratio would be useful for genetic counseling in patients who are suspected to have LS, though the genetic backgrounds for the pathogenesis of LLS need further investigation.PMID:38615286 | DOI:10.1007/s10147-024-02518-y

Source: Clinical Colorectal Cancer - April 14, 2024 Category: Cancer & Oncology Authors: Tetsuya Ito Tatsuro Yamaguchi Kensuke Kumamoto Okihide Suzuki Noriyasu Chika Satoru Kawakami Tomonori Nagai Tsukasa Igawa Kenji Fujiyoshi Yoshito Akagi Tomio Arai Kiwamu Akagi Hidetaka Eguchi Yasushi Okazaki Hideyuki Ishida Source Type: research