Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantationlburtchbuusThu, 01/11/2024 - 11:41Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantationImageDeepta Bhattacharya, who is on the University of Arizona Health Sciences Center for Advanced Molecular and Immunological Therapies advisory council, is a professor of immunobiology in the UArizona College of Medicine – Tucson.UArizona Health SciencesJan. 16, 2024Byline AffiliationUniversity of Arizona Health SciencesOne of the biggest barriers to regenerative medicine is immunological rejection by the recipient, a problem researchers at theUniversity of Arizona Health Sciences are one step closer to solving after genetically modifying pluripotent stem cells to evade immune recognition.The study"Engineering Human Pluripotent Stem Cell Lines to Evade Xenogeneic Transplantation Barriers" waspublished in the journal Stem Cell Reports last week.Pluripotent stem cells can turn into any type of cell in the body. The findings offer a viable path forward for pluripotent stem cell-based therapies to restore tissues that are lost in diseases such as Type 1 diabetes or macular degeneration."There has been a lot of excitement for decades around the field of pluripotent stem cells and regenerative medicine," said principal investigatorDeepta Bhattacharya, a professor in theUArizona College of Medicine – Tucson’sDepartment of Im...
Source: The University of Arizona: Health - Category: Universities & Medical Training Authors: Source Type: research