The generation of glioma organoids and the comparison of two culture methods

ConclusionThe success rates of the Matrigel and microtumor methods were 45.5% and 60.5%, respectively. The microtumor method had a higher success rate, shorter establishment time, more convenient passage and cryopreservation methods, better simulation of the cellular and histological characteristics of the parent tumor, and a high genetic guarantee.

Source: Cancer Medicine - March 8, 2024 Category: Cancer & Oncology Authors: Yang Zhang, Yunxiang Shao, Yanyan Li, Xuetao Li, Xuewen Zhang, Qinzhi E, Weichao Wang, Zuoyu Jiang, Wenjuan Gan, Yulun Huang Tags: RESEARCH ARTICLE Source Type: research