Physiological Evidence and Therapeutic Outcomes of Vitamin D on Cardiovascular Diseases

Curr Cardiol Rev. 2024 Jan 18. doi: 10.2174/011573403X263417231107110618. Online ahead of print.ABSTRACTVitamin D hormone is an important regulator of various physiological functions, and its deficiency is characterized by an imbalance in parathyroid hormone and calcium homeostasis. The role of vitamin D in cardiovascular physiology is well demonstrated in animal and humanbased studies. In this context, hyperlipidemia, increased atherogenic plaques, cardiac inflammation, hypertension, myocarditis, myocardial infarction, and heart failure are some of the commonest known conditions connected with vitamin D deficiency. Supplementation of vitamin D is recommended to achieve normal serum vitamin D concentrations, nonetheless, in clinical trials often seen discrepancies concerning the supplementation effects and effectiveness. This review summarizes the data on the role of vitamin D in cardiovascular health along with some recent clinical findings regarding the effects of vitamin D supplementation.PMID:38243935 | DOI:10.2174/011573403X263417231107110618
Source: Current Cardiology Reviews - Category: Cardiology Authors: Source Type: research