Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne

ConclusionThe tumor spectrum and age of onset found in this study showed that tumors other than BC had low disease penetrance inTP53 PV carriers identified using the GC-HBOC criteria for genetic testing.

Source: Cancer Medicine - January 17, 2024 Category: Cancer & Oncology Authors: K. Kast, K. Rhiem, M. Larsen, B. Wappenschmidt, R. Schmutzler Tags: RESEARCH ARTICLE Source Type: research