A prospective study of circulating estrogen in oral leukoplakia and oral squamous cell carcinoma

CONCLUSION: This study proved that irrespective of the gender bias, the female sex hormone, estradiol levels were significantly raised in OSCC patients. This study suggests that E2 may play a vital role in determining the patient prognosis in OSCC with tobacco habit. The confounding results of this preliminary study opened up new advents emphasizing the role of E2 in OSCC. The role of E2 in estrogen receptor regulation can also be a subject of study for targeted therapies in improving the patient's prognosis.PMID:38102904 | DOI:10.4103/jcrt.jcrt_2377_22
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research