GDF ‐15 and the Effect of Empagliflozin in Heart Failure: Findings from the EMPEROR Program

ConclusionsGDF-15 is a marker of worse heart failure severity, is an independent predictor of major heart failure outcomes and may be associated with more pronounced benefits of empagliflozin. GDF-15 is increased among metformin users, and empagliflozin was associated with an increase in GDF-15 levels, primarily in patients not receiving metformin.This article is protected by copyright. All rights reserved.

Source: European Journal of Heart Failure - November 15, 2023 Category: Cardiology Authors: Jo ão Pedro Ferreira, Milton Packer, Javed Butler, Gerasimos Filippatos, Stuart J. Pocock, James L. Januzzi, Naveed Sattar, Sandra González Maldonado, Marina Panova‐Noeva, Mikhail Sumin, Serge Masson, Stefan D. Anker, Faiez Zannad Tags: Research Article Source Type: research