Independent Causal Effect of Remnant Cholesterol on Atherosclerotic Cardiovascular Outcomes: A Mendelian Randomization Study

CONCLUSIONS: This large-scale Mendelian randomization study showed a robust genetic causal association between RC and cardiovascular outcomes. The effect on CAD and MI is independent of LDL cholesterol. Early screening for RC along with long-term inhibition of RC should be the focus of future therapeutic interventions.PMID:37439258 | DOI:10.1161/ATVBAHA.123.319297

Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 13, 2023 Category: Cardiology Authors: Eliano P Navarese Donna Vine Spencer Proctor Klaudyna Grzelakowska Sergio Berti Jacek Kubica Paolo Raggi Source Type: research