Characterization of neuroinflammation pattern in anti-LGI1 encephalitis based on TSPO PET and symptom clustering analysis

CONCLUSIONS: Anti-LGI1 encephalitis had a distinctive molecular imaging pattern presented by TSPO PET scan. LGI1-AIE patients with higher retention of [18F]DPA-714 in the frontal cortex were more prone to present with GTC seizures. Further studies are required for verifying its value in clinical application.PMID:36929211 | DOI:10.1007/s00259-023-06190-8

Source: Molecular Medicine - March 17, 2023 Category: Molecular Biology Authors: Jingguo Wang Jingjie Ge Lei Jin Bo Deng Weijun Tang Hai Yu Xiang Zhang Xiaoni Liu Le Xue Chuantao Zuo Xiangjun Chen Source Type: research