PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples

CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030

Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research