Late effects of childhood cancer recorded at a single outpatient clinic over the course of one year: implications for the follow-up care

Neoplasma. 2022 Jul 13:220531N584. doi: 10.4149/neo_2022_220531N584. Online ahead of print.ABSTRACTSystematic registration and analysis of detailed treatment data and data on late effects in survivors of childhood cancer are important both for building the evidence base for future assessment of current innovative therapies in pediatric oncology and for personalization of preventive care for survivors of childhood cancer. The paper provides a descriptive analysis of medical data (diagnosis, treatment, late effects, and health status) and selected patient-reported outcomes (mental health and psychosocial well-being) from a study group of 133 survivors of childhood cancer. We recruited for the study a consecutive series of survivors who attended an outpatient Late Effects Clinic at St. Anne's University Hospital in Brno, Czech Republic for a follow-up appointment over the course of one year (between March 2021 and February 2022) and met the study criteria. The enrolled survivors had been diagnosed with childhood cancer in the period 1979-2016. The average age in the sample was 27.9 years (18-53 years). We extracted and categorized the participants' treatment data and data on relevant health outcomes, both somatic and mental, from the medical records. Patient-reported outcomes were measured using the clinic's questionnaires completed by survivors prior to medical examination at the clinic. The most frequent adverse health outcome in the study sample - found in half of the survivo...
Source: Neoplasma - Category: Cancer & Oncology Authors: Source Type: research