Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Endocr Rev. 2024 Apr 27:bnae009. doi: 10.1210/endrev/bnae009. Online ahead of print.ABSTRACTThe 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms of action suggest links with conditions that do not depend only on reduced solar exposure or diet intake and that can be detected with distinctive noncanonical vitamin D metabolites. Optimal 25-hydroxyvitamin D (25(OH)D) levels remain debated. Varying recommendations from different societies arise from evaluating ...
Source: ENDOCR REV - April 27, 2024 Category: Endocrinology Authors: Andrea Giustina John P Bilezikian Robert A Adler Giuseppe Banfi Daniel D Bikle Neil C Binkley Jens Bollerslev Roger Bouillon Maria Luisa Brandi Felipe F Casanueva Luigi di Filippo Lorenzo M Donini Peter R Ebeling Ghada El-Hajj Fuleihan Angelo Fassio Stefa Source Type: research
Uterine fibroids in women diagnosed with acromegaly: a systematic review
Rev Endocr Metab Disord. 2024 Apr 26. doi: 10.1007/s11154-024-09883-z. Online ahead of print.ABSTRACTThe review discusses the relationship between acromegaly and uterine fibroids. It highlights variations in research methodologies and inconsistent findings, emphasizing the complex nature of fibroid development and the role of the somatotropic axis. Additionally, it addresses demographic factors and examines the potential impact of therapies on the risk and prevalence of uterine fibroids in individuals with acromegaly. We conducted an analysis of previously published literature that examined the repercussions of acromegaly ...
Source: ENDOCR REV - April 26, 2024 Category: Endocrinology Authors: Konrad G órski Stanis ław Zgliczyński Maria Stelmachowska-Bana ś Izabella Czajka-Oraniec Wojciech Zgliczy ński Micha ł Ciebiera Magdalena Zgliczy ńska Source Type: research
Uterine fibroids in women diagnosed with acromegaly: a systematic review
Rev Endocr Metab Disord. 2024 Apr 26. doi: 10.1007/s11154-024-09883-z. Online ahead of print.ABSTRACTThe review discusses the relationship between acromegaly and uterine fibroids. It highlights variations in research methodologies and inconsistent findings, emphasizing the complex nature of fibroid development and the role of the somatotropic axis. Additionally, it addresses demographic factors and examines the potential impact of therapies on the risk and prevalence of uterine fibroids in individuals with acromegaly. We conducted an analysis of previously published literature that examined the repercussions of acromegaly ...
Source: ENDOCR REV - April 26, 2024 Category: Endocrinology Authors: Konrad G órski Stanis ław Zgliczyński Maria Stelmachowska-Bana ś Izabella Czajka-Oraniec Wojciech Zgliczy ński Micha ł Ciebiera Magdalena Zgliczy ńska Source Type: research
Diagnostic and therapeutic use of oral micronized progesterone in endocrinology
Rev Endocr Metab Disord. 2024 Apr 23. doi: 10.1007/s11154-024-09882-0. Online ahead of print.ABSTRACTProgesterone is a natural steroid hormone, while progestins are synthetic molecules. In the female reproductive system, progesterone contributes to the control of luteinizing hormone and follicle-stimulating hormone secretion and their pulsatility, via its receptors on the kisspeptin, neurokinin B, and dynorphin neurons in the hypothalamus. Progesterone together with estradiol controls the cyclic changes of proliferation and decidualization of the endometrium; exerts anti-mitogenic actions on endometrial epithelial cells; r...
Source: ENDOCR REV - April 23, 2024 Category: Endocrinology Authors: Eleni Memi Polina Pavli Papagianni Maria Nikolaos Vrachnis George Mastorakos Source Type: research
Diagnostic and therapeutic use of oral micronized progesterone in endocrinology
Rev Endocr Metab Disord. 2024 Apr 23. doi: 10.1007/s11154-024-09882-0. Online ahead of print.ABSTRACTProgesterone is a natural steroid hormone, while progestins are synthetic molecules. In the female reproductive system, progesterone contributes to the control of luteinizing hormone and follicle-stimulating hormone secretion and their pulsatility, via its receptors on the kisspeptin, neurokinin B, and dynorphin neurons in the hypothalamus. Progesterone together with estradiol controls the cyclic changes of proliferation and decidualization of the endometrium; exerts anti-mitogenic actions on endometrial epithelial cells; r...
Source: ENDOCR REV - April 23, 2024 Category: Endocrinology Authors: Eleni Memi Polina Pavli Papagianni Maria Nikolaos Vrachnis George Mastorakos Source Type: research
Diagnostic and therapeutic use of oral micronized progesterone in endocrinology
Rev Endocr Metab Disord. 2024 Apr 23. doi: 10.1007/s11154-024-09882-0. Online ahead of print.ABSTRACTProgesterone is a natural steroid hormone, while progestins are synthetic molecules. In the female reproductive system, progesterone contributes to the control of luteinizing hormone and follicle-stimulating hormone secretion and their pulsatility, via its receptors on the kisspeptin, neurokinin B, and dynorphin neurons in the hypothalamus. Progesterone together with estradiol controls the cyclic changes of proliferation and decidualization of the endometrium; exerts anti-mitogenic actions on endometrial epithelial cells; r...
Source: ENDOCR REV - April 23, 2024 Category: Endocrinology Authors: Eleni Memi Polina Pavli Papagianni Maria Nikolaos Vrachnis George Mastorakos Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Rev Endocr Metab Disord. 2024 Apr 10. doi: 10.1007/s11154-024-09879-9. Online ahead of print.ABSTRACTThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy partic...
Source: ENDOCR REV - April 10, 2024 Category: Endocrinology Authors: Nicholas Kofi Adjei Florence Samkange-Zeeb Daniel Boakye Maham Saleem Lara Christianson Mihiretu M Kebede Thomas L Heise Tilman Brand Oluwaseun B Esan David C Taylor-Robinson Charles Agyemang Hajo Zeeb Source Type: research
