Kidney Injury in Critically Ill Patients Treated with Vancomycin and Zosyn or an Alternative: A Systematic Review and Meta-Analysis
Conclusions: Zosyn plus vancomycin is associated with more risk of AKI compared with Alt+V coverage in ICU adult populations. However, the conclusions were limited by the retrospective nature of the studies, high bias of included articles, and heterogeneity of the included studies.PMID:35736797 | DOI:10.1089/sur.2022.128 (Source: Hand Surgery)
Source: Hand Surgery - June 23, 2022 Category: Surgery Authors: Elizabeth E Blears John Morris Daniel Popp Jong O Lee William B Norbury Source Type: research
Kidney Injury in Critically Ill Patients Treated with Vancomycin and Zosyn or an Alternative: A Systematic Review and Meta-Analysis
Conclusions: Zosyn plus vancomycin is associated with more risk of AKI compared with Alt+V coverage in ICU adult populations. However, the conclusions were limited by the retrospective nature of the studies, high bias of included articles, and heterogeneity of the included studies.PMID:35736797 | DOI:10.1089/sur.2022.128 (Source: Hand Surgery)
Source: Hand Surgery - June 23, 2022 Category: Surgery Authors: Elizabeth E Blears John Morris Daniel Popp Jong O Lee William B Norbury Source Type: research
Kidney Injury in Critically Ill Patients Treated with Vancomycin and Zosyn or an Alternative: A Systematic Review and Meta-Analysis
Surgical Infections, Ahead of Print. (Source: Surgical Infections)
Source: Surgical Infections - June 23, 2022 Category: Surgery Authors: Elizabeth E. Blears John Morris Daniel Popp Jong O. Lee William B. Norbury Source Type: research
Myelodysplastic syndrome in a case of new ‐onset pancytopenia
We report the case of new-onset pancytopenia following administration of a COVID-19 vaccine and recurrent Zosyn use who was later found to have myelodysplastic syndrome. (Source: Clinical Case Reports)
Source: Clinical Case Reports - March 4, 2022 Category: General Medicine Authors: Ian Lancaster,
Deep Patel,
Vikas Sethi,
Weston Connelly,
Joseph Namey Tags: CASE REPORT Source Type: research
Negative pressure pulmonary oedema due to rigors and chills associated with liver abscess
Negative pressure pulmonary oedema (NPPE) is caused by upper airway obstruction and rapid negative pressure due to inspiratory efforts against an obstruction in a patient with preserved ejection fraction. NPPE is a perioperative life-threatening emergency, but it is rarely diagnosed and reported due to unfamiliarity. Here, we discuss the case of a patient who developed acute respiratory failure with bacteraemia due to NPPE after an intense inspiratory effort against transient laryngeal dyskinesia. AbstractA 61-year-old male presented with progressive generalized weakness, myalgia, diaphoresis, fever, episodic chills and ri...
Source: Respirology Case Reports - August 23, 2021 Category: Respiratory Medicine Authors: Haroon Chaudhry,
Swathi Nimmala,
Bhavani Nagendra Papudesi,
Fizza Sajjad,
Sanu Paul,
Zimran Gohar,
Reuben Azad,
Hannah Naveen,
Joseph Demidovich Tags: CASE REPORT Source Type: research
Ventilator associated pneumonia in surgical and medical icu's in urban tertiatry care centre hospital
Conclusion: The high rates of VAP in this study indicates the need for active infection control & implementation of guidelines for infection prevention which will ensure improved patient safety in the ICUs and judicious use of antibiotics should be practiced . (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Mathew, T., Mishra, B., Mathew, B. Tags: Respiratory infections Source Type: research
Management of Expander- and Implant-Associated Infections in Breast Reconstruction
ConclusionRisk factors for explantation due to postoperative periprosthetic infections following TE/implant-based breast reconstruction include chemotherapy, hypertension and therapeutic mastectomy. Prompt diagnosis and effective treatment of periprosthetic infection, particularly in these high-risk patients, are imperative to salvage the breast reconstruction. Gram-negative bacteria are increasingly found in breast implant infections and should be covered when employing empiric antibiotherapy.Level of Evidence IVThis journal requires that authors assign a level of evidence to each article. For a full description of these ...
Source: Aesthetic Plastic Surgery - August 24, 2020 Category: Cosmetic Surgery Source Type: research
Generalized fixed drug eruption to piperacillin/tazobactam and review of literature
Fixed drug eruption (FDE) is an adverse drug reaction characterized by the development of well-circumscribed, round, dusky erythematous macules and plaques on cutaneous or mucosal surfaces. The reaction occurs on the same mucosal or cutaneous site with subsequent exposures to the offending drug. Although FDE usually manifests as a single lesion, in rare instances, more than one lesion may arise and this is referred to as a generalized eruption. Herein, we present a 31year-old man with history of cystic fibrosis who developed a generalized fixed drug eruption to piperacillin/tazobactam (Zosyn, Pfizer). We discuss our patien...
Source: Dermatology Online Journal - June 12, 2018 Category: Dermatology Source Type: research
Generalized fixed drug eruption to piperacillin/tazobactam and review of literature.
Abstract
Fixed drug eruption (FDE) is an adverse drug reaction characterized by the development of well-circumscribed, round, dusky erythematous macules and plaques on cutaneous or mucosal surfaces. The reaction occurs on the same mucosal or cutaneous site with subsequent exposures to the offending drug. Although FDE usually manifests as a single lesion, in rare instances, more than one lesion may arise and this is referred to as a generalized eruption. Herein, we present a 31year-old man with history of cystic fibrosis who developed a generalized fixed drug eruption to piperacillin/tazobactam (Zosyn, Pfiz...
Source: Dermatol Online J - April 15, 2018 Category: Dermatology Authors: Kornmehl H, Gorouhi F, Konia T, Fung MA, Tartar DM Tags: Dermatol Online J Source Type: research
Severe Symptoms, but a Truly Treatable Disease
BY NOURA MAHDI; DARRON LEWIS; JEREMY OSBORNE; & AHMED RAZIUDDIN, MDA 73-year-old man was brought to the emergency department from his nursing home for rectal bleeding and anemia. The patient mentioned he had had episodes of bright red rectal bleeding and constipation for a few months. A colonoscopy had been done prior to the visit, which revealed a large intestine tumor and biopsy confirming adenocarcinoma. He was awaiting an appointment with his surgeon.The patient reported bloody rectal leakage, and a CBC done at the nursing home showed a hemoglobin level of 7.2. He also complained of dyspnea but denied any other ...
Source: The Case Files - March 20, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research
Piperacillin-induced Thrombocytopenia in a Dual Heart and Kidney Transplant Patient: A Case Report
The present study reports a case of piperacillin-induced thrombocytopenia in a dual heart and kidney transplant patient on January 28, 2016 (taking mycophenolate mofetil and tacrolimus). Before the transplant, the patient was treated with Zosyn twice, with no reports of thrombocytopenia or allergy. However, he was diagnosed with heparin-induced thrombocytopenia and vancomycin allergy during each of those hospitalizations, respectively. Eight months after the transplant, the patient presented with infectious symptoms and was started on Zosyn. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - August 4, 2017 Category: Transplant Surgery Authors: S. Patel, R. Levin-Epstein, J. Kobashigawa Source Type: research
Treatment of a High-Risk Diabetic Patient with Peripheral Vascular Disease and Osteomyelitis
We report a case of calcaneal osteomyelitis that was surgically resected from a patient with diabetes and peripheral vascular disease. A 91-year-old male with history of type 2 diabetes, peripheral vascular disease, balloon angioplasty, and recent (2 months ago) stent of the superficial femoral artery presented to the emergency department with a left heel wound infection probed to bone. The patient reported having been on intravenous Zosyn for several months via an outside infectious disease provider for clinical suspicion of osteomyelitis, but noted no improvement. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - May 30, 2016 Category: Radiology Authors: Latricia L. Allen, Garrett Kalmar, Vickie R. Driver Source Type: research
P17: pneumomediastinum a rare complication of colonoscopy polypectomy successfully treated with conservative management
Conclusions
Though complications from polypectomies are rare, they can be associated with a high morbidity and mortality but rarely associated with pneumomediastinum and in certain stable patients can be treated with conservative management. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - February 25, 2016 Category: Research Authors: Rives, C., Pourmorteza, M., Carter, E., Young, M. Tags: Display Posters, Wednesday, April 13, 2016 Source Type: research
Visual and absorbance analyses of admixtures containing vancomycin and piperacillin-tazobactam at commonly used concentrations.
CONCLUSION: Visual, microscopic, and absorbance analyses showed no evidence of incompatibility when piperacillin-tazobactam 33.75-90 mg/mL was combined with vancomycin ≤7 mg/mL. Reversible and irreversible precipitates formed when piperacillin-tazobactam was combined with vancomycin ≥8 mg/mL.
PMID: 26843502 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 9, 2016 Category: Drugs & Pharmacology Authors: O'Donnell JN, Venkatesan N, Manek M, Rhodes NJ, Scheetz MH Tags: Am J Health Syst Pharm Source Type: research
