Erythematous scaly plaques and nodules on scalp
We describe a 45-year-old man who presented with erythematous scaly plaques and nodules on his scalp. In previously reported cases, there were only descriptions of nodules as well as tumors. However, in our case, the patient presented with plaques and nodules on his scalp that quickly resolved with treatment for syphilis. It is important to recognize and treat syphilis at an early stage. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - November 3, 2023 Category: Dermatology Authors: Ho, Peiying Audrey Source Type: research
Underemphasis of histopathology training in the micrographic fellowship application process
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Sarlin, Samantha Source Type: research
Livedoid vasculopathy
is a painful thrombo-occlusive vascular disorder characterized by spontaneous thrombosis in medium-size arterioles, which causes localized hypoxia and skin ulceration. As livedoid vasculopathy is rare, case reports are the primary means of expanding collective knowledge about its presentation and response to various therapies. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Leeolou, Melissa C Source Type: research
Secondary syphilis presenting as leukocytoclastic vasculitis in a 61-year-old man
We report a case of secondary syphilis presenting with an acute, rapidly progressive purpuric eruption mimicking leukocytoclastic vasculitis. A 61-year-old man presented with a 6-day history of nonpruritic rash on his chest and lower extremities associated with fatigue, sore throat, and night sweats. Examination revealed purpuric papules, extending from the dorsal feet to the hips; mucosal surfaces were not involved. A diagnosis of cutaneous small-vessel... (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Mohamed, Nada Source Type: research
We hardly knew ye... goodbye, #dermtwitter?
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Kennedy, Jake Source Type: research
Two congenital cases of pigmented epithelioid melanocytoma with unique clinical and genetic features
We report two unique cases of congenital PEM with PRKCA fusion transcripts: a multifocal PEM with an aggressive incompletely resectable scalp tumor and a solitary palmar PEM with newly reported ITGB5-PRKCA fusion. Through these case reports and a summary of previously reported cases, we outline the spectrum of disease of PEM and highlight the key clinical and histopathologic features associated with PEM with PRKCA fusion transcripts. We also discuss the treatment options and suggest that surgical excision without further adjuvant systemic treatment is reasonable first-line therapy given the favorable prognosis. (Source: De...
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Zaaroura, Hiba Source Type: research
Generalized perforating granuloma annulare associated with latent tuberculosis successfully treated with isoniazid: case report and review
We report a 66-year-old woman who presented with a 7-month history of mostly asymptomatic generalized infiltrated, flesh-colored to red-brown umbilicated or crusted papules. Histopathological findings were compatible with perforating granuloma annulare. Diagnostic workup revealed latent tuberculosis. To the best of our knowledge, this is the second published case of GPGA associated with latent tuberculosis and the first one that was successfully treated by isoniazid... (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Kapetanovic, Igor Source Type: research
Prescription trends of antidepressant, anxiolytic, and anticonvulsant medications among dermatologists from 2013 to 2020
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Roster, Katie Source Type: research
Erythema elevatum diutinum in a patient with rheumatoid arthritis
We report a 65-year-old woman with painful and itchy lesions on her elbows, hands, knees, and foot for a year. Histopathologic examination confirmed the diagnosis of erythema elevatum diutinum and treatment with dapsone produced significant clinical improvement within few weeks. Erythema elevatum diutinum is a rare disease that should be considered in patients with violaceous nodular plaques located over the extensor regions of the limbs. Knowledge of this unusual pathology and its association helps to avoid misdiagnosis and late treatment. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Bittencourt, Maraya Semblano Source Type: research
Assessment and quality improvement of the Community Care Network: Veterans Administration (VA) patient access to community Mohs micrographic surgery
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Chattopadhyay, Aheli Source Type: research
A case series of hydroxychloroquine exacerbating the dermatomyositis rash
Hydroxychloroquine (HCQ) is an antimalarial agent that is commonly used in the management of rheumatic skin disease. Few reports exist documenting exacerbation of dermatomyositis (DM) related to HCQ. Herein, we describe three adult patients with worsening DM cutaneous disease after starting HCQ and resolution or improvement with cessation. The time to exacerbation ranged from two weeks to nine months after the initiation of HCQ 400mg/day. Two of the three patients had antibodies to transcription intermediary factor 1 γ (TIF1γ) and the other had antibodies to anti-nuclear matrix protein 2 (NXP2). After discontinuation of ...
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Rypka, Katelyn Source Type: research
Cutaneous metastasis as a first sign of adenocarcinoma of the cervix
We present a patient whose cutaneous signs led to the diagnosis of metastatic adenocarcinoma of the cervix. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Gociman, Shadai Source Type: research
Anti-laminin 332 antibodies in graft-versus-host disease-associated bullous pemphigoid after allogeneic peripheral blood stem cell transplantation
We report a 48-year-old woman with bullous pemphigoid (BP) with antibodies against the B3 subunit of laminin 332 after the development of graft-versus-host disease (GVHD). She was diagnosed with recurrent acute lymphoblastic leukemia at 40 years of age and underwent two rounds of allogeneic peripheral blood stem cell transplantations (PBST). Two and a half years after the second PBST, multiple tense blisters appeared on her face, hands, and lower legs. The diagnosis of BP was based on hematoxylin eosin and immunofluorescence staining and immunoblotting analyses. A combination regimen of topical corticosteroids (clobetasol ...
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Hida, Yasutoshi Source Type: research
A case of monkeypox and cytomegalovirus coinfection manifesting with crusted lesions mimicking rupiod syphilis
We present a 41-year-old man patient with untreated HIV with generalized rupioid crusted ulcerated plaques with perineal ulceration that were found to represent monkeypox and cytomegalovirus infections. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Zevallos, Jean Source Type: research
Ficus carica L photodermatitis: a report of five cases with histopathologic study and review of the literature.
We present five cases of photodermatitis caused by contact with Ficus carica L and subsequent exposure to sunlight. A histopathologic study and review of the literature are included. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - October 26, 2023 Category: Dermatology Authors: Veraldi, Stefano Source Type: research
