Successful outcome of psoriasis in a laryngeal cancer patient treated with ixekizumab, a possible beneficial treatment for both pathologies
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 16, 2021 Category: Dermatology Source Type: research

The spectrum of focal epithelial hyperplasia-a report of two cases
Focal epithelial hyperplasia is a rare, benign, and asymptomatic disorder, characterized by soft papules on the oral cavity. It is primarily associated with human papillomavirus genotypes 13 and 32. It most commonly affects children and young adults. When it affects young adults, it is important to differentiate it from oral condyloma acuminata. Its diagnosis may be made clinically, but histologic examination and PCR genotyping are often useful. Treatment is not always mandatory. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Leukemia cutis and eccrine squamous syringometaplasia
We report a 75-year-old man who developed ESS within lesions of leukemia cutis (LC). The patient had an inaugural diagnosis of acute myeloid leukemia (AML) and he was not on chemotherapy when the biopsy was performed. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Painful scrotal dermatitis secondary to topical 5-fluorouracil
We present a patient who developed a painful scrotal dermatitis after applying the topical cream to actinic keratoses on his chest. Upon discontinuation of topical 5-FU, the reaction resolved over a four-week period with oral prednisone and topical betamethasone ointment. The patient was re-challenged with topical 5-FU one year later and again developed scrotal pain and erythema similar to the initial reaction. Scrotal dermatitis is a rare adverse effect of topical 5-FU therapy that can be associated with significant distress and disruption of daily activities. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

An unusual case of keratinopathic icthyosis: a diagnostic conundrum
We report an intriguing case of KI presenting as generalized ichthyosis in a reticulate pattern surrounding islands of normal skin, epidermolytic hyperkeratosis and binucleate cells on histopathology, and heterozygous mutation in KRT10. Through this case, we would like to demonstrate the importance of genetic studies and genotype-phenotype correlation in diagnosing such challenging cases. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Effect of pre-operative informational video on Mohs surgery patient experience
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Familial multiple basaloid follicular hamartoma
We present a case of FMBFH presenting in adulthood, which was treated with CO2 laser with satisfactory results. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Disseminated atypical mycobacterial infection in an allogeneic stem cell transplant recipient
We present an immunocompromised patient with disseminated cutaneous mycobacterial infection with digital tenosynovitis. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

The various treatment modalities of dermatofibrosarcoma protuberans
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

An abdominal skin lesion: to lump or split? a case presentation
We describe a 41-year-old man with recently diagnosed HIV who was admitted for acute right vision loss and a diffuse rash with involvement of the palms and soles. He received diagnoses of secondary syphilis and Kaposi sarcoma in the setting of AIDS. Examination revealed an unusual dark brown-to-purple umbilicated papule with a necrotic center on the abdomen, raising a diagnostic dilemma. Skin biopsy showed secondary syphilis, despite the concurrent diagnosis of Kaposi sarcoma. The patient was treated with antibiotic and antiretroviral therapy and symptoms resolved. This case aims to share the clinical reasoning behind diag...
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Prevention of surgical site infection using 2-octylcyanoacrylate following Mohs micrographic surgery: case series in a high-risk patient population
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Glomangioma of the elbow
We present a patient with a painful, mobile nodule on the elbow. The nodule was skin-colored and had no punctum or discharge. It was excised and histopathology showed that the lesion was a glomangioma, or glomuvenous malformation. This is a neoplasm that arises from the glomus body, a thermoregulatory neurovascular structure. The glomus body is composed of glomus cells, vascular cells, and smooth muscle cells. Three subtypes of neoplasms may arise from the glomus body, depending on the extent to which they involve the three types of cells. They include glomus tumors, glomangiomas/glomuvenous malformations, and glomangiomyo...
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

The impact of the coronavirus disease 2019 pandemic on dermatologist burnout: a survey study
Burnout in dermatology is on the rise, with 36% of U.S. dermatologists experiencing burnout in 2020. The coronavirus disease 2019 (COVID-19) pandemic may exacerbate this problem with healthcare workers reporting increased anxiety, depression, and insomnia. To assess the rate, severity, and causes of burnout before and during the pandemic, a survey was sent to academic dermatologists through the Association of Professors of Dermatology (APD) listserv and compared to a similar survey administered to the same population prior to the pandemic. Burnout rates have increased from 2018, with 53% of participants experiencing burnou...
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Acquired unilateral facial melanocytosis: nevus of Sun
In this report, we describe a rare case of acquired unilateral facial melanocytosis, also called nevus of Sun, in a Caucasian woman. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Exfoliative cheilitis related to psychologic factors uncovered during primary immunodeficiency evaluation
A 40-year-old previously healthy, non-atopic woman was referred for evaluation of a possible immunodeficiency disorder in the setting of an unusual erosive cheilitis and history of recurrent methicillin-resistant Staphylococcus aureus (MRSA) infection. Extensive work-up was non-diagnostic, including screening for immunologic disorders. She had failed multiple therapeutic modalities, including corticosteroid and immunosuppressive therapy. Tissue biopsy from the lip proved pivotal in demonstrating changes suggestive of factitial disease. This led to further detailed history-taking, yielding evidence of considerable psycholog...
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

How should medical students prepare for a clinical dermatology rotation?
Skin diseases are commonly encountered in medical practice, yet medical students often receive little dermatology training. There is little research on what self-study materials best prepare students. We aim to identify which resources dermatology residents have found to be most useful in preparing for clinical dermatology rotations and dermatology residency. Forty current dermatology residents and fellows responded to our REDCap-generated survey. Data was analyzed using descriptive statistics. Most respondents (N=36, 90%) reported using outside resources to prepare for clinical dermatology rotations and dermatology reside...
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Endocrine mucin-producing sweat gland carcinoma of the cheek
We report a 90-year-old man who had a hard, dome-shaped tumor approximately 9 mm in diameter on the left cheek. Dermoscopy showed an overall, non-uniformly light-pink tumor with crust. The diagnosis of EMPSGC is made histologically from excisional biopsy. No signs of recurrent disease were evident at 42 months postoperatively. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Adalimumab for treatment of severe ulcerative sarcoidosis
We describe severe ulcerative sarcoidosis in a 60-year-old woman with chronic ulcerative necrobiosis lipoidica-like plaques on her left arm for over 20 years. Her condition had not responded to previous treatments with hydroxychloroquine, methotrexate, and sulfasalazine. After a four-month course of adalimumab therapy in addition to pentoxifylline and prednisone with taper, the patient had significant improvement in her skin disease. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Cost-effectiveness of skin biopsies performed by non-physician clinicians for Medicare beneficiaries
An increasing number of non-physician clinicians (NPCs) are providing dermatologic care. We compared the cost-effectiveness of skin biopsies performed by dermatologists and dermatology NPCs using publicly-available Medicare claims data and numbers needed to biopsy (NNBs) published in the literature. We estimated that dermatology NPCs performed slightly greater mean numbers of skin biopsies per beneficiary (0.51 versus 0.47) at a lower payment per biopsy ($44.93 versus $55.10) as compared to dermatologists. However, we estimated a higher mean cost per malignancy diagnosed by dermatology NPCs relative to dermatologists (rang...
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Social media use in residency recruitment during the COVID-19 pandemic
To investigate the extent to which dermatology programs use social media to connect with applicants, we conducted a search of all 140 residency programs on Instagram, Facebook, Twitter, and YouTube. Our search revealed 74 (53%) Instagram, 21 (15%) Facebook, 20 (14%) Twitter, and four (3%) YouTube accounts for dermatology programs, with the number of Instagram accounts increasing five-fold from the end of 2019 to present. Our results demonstrate that conditions created during the coronavirus disease 2019 (COVID-19) pandemic accelerated dermatology residency programs' acceptance of social media, particularly Instagram, as a ...
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Pilomatrix carcinoma: a rare cutaneous adnexal tumor.
Pilomatrix carcinoma is a rare tumor that is generally not diagnosed clinically. An 80-year-old man presented with a 5-month history of rapidly growing nodule of the submandibular area. Histological examination revealed a pilomatrix carcinoma, an aggressive malignancy with metastatic potential (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - July 8, 2021 Category: Dermatology Source Type: research

Giant chondroid syringoma on the upper lip: a case report
We present a 65-year-old man with a chronic, indolent, subcutaneous tumor with upper lip deformity. An excisional biopsy was performed under local anesthesia. Based on histopathological analysis, the resected lesion was identified as a chondroid syringoma of the apocrine type. There was no recurrence during the one-year follow-up after surgery. The occurrence of a large chondroid syringoma in the upper lip is rare. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 12, 2021 Category: Dermatology Source Type: research

Granular cell tumor: importance of histopathology in determining malignant potential
Granular cell tumors (GCTs), sometimes called Abrikossoff tumors, are rare and typically benign soft tissue tumors. Malignant GCTs, which are even rarer than benign GCTs, can occur and must be detected early given their high mortality rate. Distinguishing between benign and malignant GCTs is difficult clinically; however, histologic evaluation plays an essential role in this endeavor. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

A solitary lesion of idiopathic calcinosis cutis in an infant: subepidermal nodular calcinosis or milia-like idiopathic calcinosis cutis?
Milia-like idiopathic calcinosis cutis (MICC) and subepidermal calcified nodule (SCN) are described as different entities under the heading of idiopathic calcinosis cutis. Although there are some clinical differences, they share many features. Whereas MICC lesions are located mostly on the extremities and rarely on the face, SCN manifests itself mostly on the face, rarely on the extremities. Milia-like idiopathic calcinosis cutis almost always presents with multiple lesions, whereas SCN shows mainly solitary and rarely multiple lesions. Association with Down syndrome (DS) has been reported in up to two-third of the cases w...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Practitioner assessment of mental health in dermatologic disease
Patients with certain dermatologic skin diseases have been found to be at increased risk for depression and suicidal ideation. As there is not much information available on mental health interventions taken in dermatologic practices, we conducted a survey to assess the extent to which dermatologists monitor and follow up with the mental health of their patients. We discovered that dermatologists are aware of mental health issues associated with these dermatologic diseases but have no standard of care for their assessment. By obtaining this information, we can enable ourselves to fill in these deficiencies to help improve p...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Perniosis in the COVID-19 era
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) and the most common symptoms include fever, dry cough, dyspnea, fatigue, anorexia, ageusia, and anosmia. Cutaneous manifestations are less common and we share our experience with an otherwise healthy and asymptomatic young man. The patient presented with painless acrocynosis of the left toes which progressed to desquamation by day 16 of disease onset. Disease progression is documented via multiple photographs that portray progression of disease and subsequent resolution over approximately six weeks. Symptomatic tre...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Gefitinib-associated lichen planus pigmentosus-like eruption
The epidermal growth factor receptor (EGFR) signaling pathway is one of the oncogenic pathways in non-small cell lung cancer. Gefitinib is classified as a first-generation EGFR-tyrosine kinase inhibitor (TKI). A variety of cutaneous adverse effects related to the drug has been reported. Cutaneous hyperpigmentation is a rare side effect of EGFR inhibitor (EGFRi). Herein, we report a 62-year-old woman with non-small cell lung carcinoma who presented with symmetrical, slate-gray-to-brownish-black macular pigmentation on sun-exposed and non-sun-exposed areas after eight months of gefitinib administration. The clinical features...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

An unusual case of multiple grouped non-familial trichoepitheliomas
We report a healthy 32-year-old woman with sporadic multiple clustered and non-segmental TEs without positive family history. There have been two other cases reported in the literature that had non-familial multiple TEs, one was facially disfiguring and the other was in a segmental pattern. Our case has been the only one reported in the English literature which has sporadic, multiple TEs clustered unilaterally and non-segmentally on the trunk. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

The effect of physician appearance on patient perceptions of treatment plans
The presentation of a physician's clothing and themselves is an important part of the physician-patient interaction. Physician attire can impact patient satisfaction and trust in their physician. We sought to discover the influence physician attire may have on patients' comfort level with proposed treatment plans, which could influence treatment adherence. We surveyed 495 subjects to better understand the relationship between physician attire and patients' perceptions of treatment plans. We found subjects' comfort level in proposed treatment plans was not significantly affected by physician attire. This finding suggests ph...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Bullous eosinophilic annular erythema
We present an unusual case of a 47-year-old patient who developed this condition. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Rural melanoma patients in Maryland do not present with more advanced disease than urban patients
Purpose: Rural populations have higher poverty rates, lower educational attainment, higher smoking rates, lower rates of health insurance, higher proportions of elderly individuals, decreased access to health services including dermatology, higher all-cause mortality, and higher mortality from melanoma. Despite these disparities, rural patients have not been adequately studied within the dermatologic literature, particularly at geographic units smaller than the county level. Methods: We used zip codes and Rural Urban Commuting Area (RUCA) codes to conduct a cross-sectional study on the prevalence and severity of melanoma a...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Combined carvedilol and gabapentin treatment induces a rapid response in red scrotum syndrome
Red scrotum syndrome (RSS) is a rare dermatologic condition characterized by persistent erythema and analgesia of the male genitalia that cannot be attributed to contact or atopic dermatitis or acute or chronic infections. Treatment of RSS is challenging since it often fails to respond to corticosteroids, antifungals, antivirals, and antibiotics. Several reports described RSS patients who responded to gabapentin, pregabalin, and ?-adrenergic receptor blockers, suggesting a neuropathic etiology. Here we present a refractory RSS case with rapid clinical improvement on a combined carvedilol plus gabapentin therapy. We suggest...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Subcutaneous metastasis from an atypical pulmonary carcinoid tumor
We report the case of a 71-year-old woman with a longstanding history of primary atypical pulmonary carcinoid tumor who presented with a new tender cutaneous nodule. Immunostaining of the nodule was consistent with metastatic atypical carcinoid tumor of the skin including positive staining for neuroendocrine markers chromogranin and synaptophysin. Dermatologists should consider cutaneous neuroendocrine metastasis when evaluating new nodules in patients with stable pulmonary carcinoid tumors or in those with concomitant concerning respiratory symptoms. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Alopecia areata in a patient with WNT10A heterozygous ectodermal dysplasia
We report a case of a patient with ectodermal dysplasia attributed to a heterozygous 321C>A mutation in WNT10A who developed overlying autoimmune mediated hair loss. To the best of our knowledge this is the first reported case of alopecia areata in a patient with WNT10A heterozygous ectodermal dysplasia. This case highlights the importance of considering multiple pathways of hair loss in patients with underlying genetic defects and raises the possibility of a shared genetic predisposition. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Interstitial granuloma annulare triggered by Lyme disease
We present a case of a man in his 60s with a three-week history of progressive targetoid plaques on his arms, legs, and trunk. Skin biopsy demonstrated interstitial granuloma annulare. Additional testing revealed IgM antibodies to Borrelia burgdorferi on western blot suggesting interstitial granuloma annulare was precipitated by the recent infection. Lyme disease is an uncommonly reported association with interstitial granuloma annulare. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Plica neuropathica in severe reactive depression: clinical and trichoscopic features
We report a case of PN in a woman with severe reactive depression and present the trichoscopic findings. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Adenoma of the nipple: a mimic of breast malignancy
We describe the clinical, dermoscopic, and histopathological findings in a patient with nipple adenoma and discuss the clinical and histological differential diagnosis as well as the different treatment options. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Mental health outcomes in White patients versus patients with skin of color with psoriasis
Objective: To evaluate the relationship between psoriasis and mental health in patients from different racial backgrounds. Methods: We performed a nationwide, cross-sectional study evaluating 7,519,662 (weighted) patients, comparing White patients versus patients with skin of color (SOC), using the 2004-2017 Medical Expenditure Panel Survey (MEPS). Results: Psychological distress (measured by Kessler 6-Item Psychological Distress Scale) was similar between White and SOC patients (4.132 [95% CI,3.679-4.586] and 3.710 [95% CI,2.932-4.488], P=0.407). Depression (measured by Patient Health Questionnaire 2) was similar between ...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Sun protection behaviors among people living with HIV
People living with HIV (PLWH) are at increased risk for both melanoma and nonmelanoma skin cancers, but there is currently no data on sun protection behaviors among PLWH. We created a 28-question paper survey to collect information on patient demographics and sun protection behaviors among PLWH. We found that although 71.6% of respondents reported spending at least 30 minutes to two hours in the sun daily, only 29.7% reported consistent use of sunscreen. In addition, 41.9% rarely or never received sunscreen counseling by their healthcare providers. There is therefore a need for increased training for healthcare providers i...
Source: Dermatology Online Journal - June 11, 2021 Category: Dermatology Source Type: research

Metastatic malignant melanoma in an endometrial polyp
We present an 81-year-old woman with metastatic melanoma confined to an endometrial polyp leading to the diagnosis of widespread dissemination of the patient's acral melanoma resected 6 years prior. Although rare, metastatic melanoma should be considered as a cause for abnormal bleeding, especially in the post-menopausal patient with a history of melanoma. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - May 14, 2021 Category: Dermatology Source Type: research

Vitiligo in a 9-year-old girl with Koolen-de Vries syndrome
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

Successful treatment of bullous pemphigoid with dupilumab: a case and brief review of the literature
We present an 80-year-old man with moderate to severe bullous pemphigoid successfully treated with dupilumab. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

Granuloma annulare on the palms
We present the case of a 72-year-old man with a one-week history of a red rash on the palms of both hands. A 4mm punch biopsy revealed interstitial granulomatous inflammation within the dermis and a colloidal iron stain showed increased dermal acid mucin. Immunohistochemical staining for CD68 confirmed the presence of abundant histiocytes within the dermis. The clinical and pathological correlation was consistent with the diagnosis of interstitial granuloma annulare. Exclusive involvement of the palms is a rare presentation and serves as a reminder for practitioners to keep granuloma annulare in their differential diagnosi...
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

Anti-MDA-5 negative, anti-Ku positive clinically amyopathic dermatomyositis
We present a patient with anti-MDA5 negative, anti-Ku positive clinically amyopathic dermatomyositis (CADM). A 61-year-old woman presented with a chief complaint of a 20-year history of a pruritic rash that was active on her face, chest, hands, legs, and back. A mildly scaly, erythematous, photo-distributed eruption along with slightly violaceous, scaly papules accentuated on the wrist, metacarpophalangeal joints, proximal interphalangeal and distal interphalangeal joints. Antibody profile was significant for positive ANA and anti-dsDNA, elevated anti-TIF-1gamma (RDL)/p155, and weakly positive anti Ku. Biopsy was consisten...
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

Semi-automated total body photography supports robust delivery of skin cancer monitoring services during the SARS-COV2/COVID-19 pandemic
Background: The SARS-CoV-2/COVID-19 pandemic dramatically impacted the delivery of healthcare, including dermatological services. In the initial stages of the pandemic, reduced patient flow produced a dramatic drop in the volume of skin cancer screening. Consistent with COVID-19 precautions, our practice conducted visual skin examinations (VSE) utilizing semi-automated total body photography (TBP). Methods: A cross-sectional study of patient characteristics and self-reported melanoma risk factors associated with TBP usage was conducted on all patients from May to November 2020 in a single practitioner private dermatology s...
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

The effect of gluten on skin and hair: a systematic review
Non-celiac gluten sensitivity is often clinically indistinguishable from celiac disease, and patients show improvement or resolution of their symptoms with a gluten-free diet. In contrast to celiac disease, the effects of gluten on the skin and hair in the context of non-celiac gluten sensitivity are not as clear. This review aims to describe the impact of gluten on the skin and hair in patients with non-celiac gluten sensitivity and those without a definitive celiac disease diagnosis. A literature search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) reporting gu...
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

Assessment of teledermatology education during residency training: a nationwide survey of residents and program directors
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

SARS-CoV-2 infection in a patient with psoriasis treated with risankizumab
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

Pembrolizumab-associated pyoderma gangrenosum in a patient with metastatic squamous cell carcinoma
Pyoderma gangrenosum (PG) is a rare, ulcerative neutrophilic dermatosis that has been reported in association with certain medications. Recognition of medications that trigger PG may help to better understand the pathogenesis of the condition and to provide earlier diagnosis and treatment for affected patients. Herein, we report a case of new-onset PG following initiation of the checkpoint inhibitor pembrolizumab for the treatment of metastatic cutaneous squamous cell carcinoma. Our case was resistant to intralesional corticosteroid therapy, but ultimately improved with systemic corticosteroids and cessation of pembrolizum...
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research

Changes in melanoma care practices during the COVID-19 pandemic: a multi-institutional cross-sectional survey
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - May 10, 2021 Category: Dermatology Source Type: research