Amyopathic dermatomyositis with TIF1? positivity treated with IVIG
We present a patient with anti-TIF1? positive amyopathic dermatomyositis associated with bilateral breast cancer. The patient was safely treated with trastuzumab for breast cancer and intravenous immunoglobulin for dermatomyositis. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - April 24, 2023 Category: Dermatology Authors: Jiang, Simon W Source Type: research
Position Title: Basic Scientist
The University of California, Davis, School of Medicine, the Department of Dermatology is currently recruiting for a full-time basic research position in the series of Ladder rank or In-Residence at the Assistant, Associate or Full Professor rank. Appointees to this position will be predominantly engaged in research, but also participate in teaching and engage in University and public service. This position may be 100% tenure track or a 50/50 appointment, in which case the position will be 50% tenure track and 50% In Residence. Professor In-Residence titles are intended to be used for individuals supported by non-State fun...
Source: Dermatology Online Journal - April 24, 2023 Category: Dermatology Authors: Department of Dermatology, The University of California, Davis School of Medicine Source Type: research
Bilateral eccrine angiomatous hamartomas of the proximal interphalangeal joints
We present a case of bilaterally symmetric, asymptomatic eccrine angiomatous hamartomas involving all proximal interphalangeal joints of both hands. To date, there are only four prior cases of bilaterally symmetric eccrine angiomatous hamartomas reported in the literature, suggesting that the distribution experienced by our patient may represent a previously undescribed syndrome. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - April 24, 2023 Category: Dermatology Authors: Nunez, M Mike Source Type: research
Cutaneous metastases revealing a second hidden neoplasm
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - April 24, 2023 Category: Dermatology Authors: de Matos, Pedro Rolo Source Type: research
A rare case of herpes zoster triggered by a non-live varicella vaccine
We describe a rare case of an immunocompetent patient with herpes zoster triggered by Shingrix, a non-live vaccine designed to protect against herpes zoster. Although herpes zoster has been described as a reaction to vaccinations before, to our knowledge this is the first report of herpes zoster triggered by a varicella zoster vaccine. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - April 24, 2023 Category: Dermatology Authors: Williams, Josiah A Source Type: research
Tumor treating fields applied to the skin as a novel adjuvant oncology treatment: allergic contact dermatitis in a patient with glioblastoma multiforme
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - April 24, 2023 Category: Dermatology Authors: Kazemi, Soroush Source Type: research
Cutaneous lymphangitis carcinomatosa: a unique presentation of a rare disease
A 75-year-old man with a three-year history of metastatic lung adenocarcinoma was diagnosed with cutaneous lymphangitic carcinomatosa of unique morphology. He was admitted to our hospital for right neck swelling, erythema, and failure to thrive. Skin examination demonstrated an indurated, thickened, firm, hyperpigmented plaque extending from the right neck and chest to the right ear, cheek, and eyelids. Skin biopsy demonstrated poorly differentiated adenocarcinoma, morphologically consistent with metastasis from the patient's known pulmonary adenocarcinoma and showed dermal invasion, perineural invasion, and involvement of...
Source: Dermatology Online Journal - April 24, 2023 Category: Dermatology Authors: Peterson, H Source Type: research
Herpetic infection in Hailey-Hailey disease
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - February 26, 2023 Category: Dermatology Authors: Lim, Subin Source Type: research
Epstein-Barr virus-positive CD30+ B-cell lymphoproliferative disease with histologic features resembling grade III lymphomatoid granulomatosis induced by methotrexate
We describe a patient with long-standing rheumatoid arthritis treated with MTX who developed cutaneous Epstein-Barr virus (EBV)-positive B cell lymphoproliferative disease resembling grade III lymphomatoid granulomatosis localized to the right leg. The lymphomatoid process resolved with withdrawal of the MTX. The pathogenesis of iatrogenic lymphoproliferative disorder was most likely triggered by the rheumatoid inflammation and the immunosuppressing effects of MTX, which led to EBV reactivation. We recommend a trial of MTX discontinuation prior to considering chemotherapy in patients with rheumatoid arthritis treated with ...
Source: Dermatology Online Journal - February 16, 2023 Category: Dermatology Authors: Quaye, Elizabeth H Source Type: research
Social support is associated with reduced impact of hidradenitis suppurativa on quality of life: an observational study
(Source: Dermatology Online Journal)
Source: Dermatology Online Journal - February 16, 2023 Category: Dermatology Authors: Singh, Rohan Source Type: research
Delayed diagnosis of DRESS syndrome in a patient with skin of color
We describe a particularly severe case of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome with hemodynamic instability, erythroderma, profound eosinophilia, and severe organ dysfunction. We attribute the severity in part to a delay in diagnosis due to patient's skin of color, as the erythroderma was not noticed until a dermatologist was consulted. This case highlights how even severe skin disease can present less conspicuously in patients with darker skin types. We outline several strategies that can help clinicians to recognize DRESS and other skin disease phenotypes in patients of color, thereby av...
Source: Dermatology Online Journal - February 16, 2023 Category: Dermatology Authors: Bean, Eric L Source Type: research
A case of self-improving collodion ichthyosis associated with a rare variant of the ALOX12B gene
Collodion baby is usually a manifestation of autosomal recessive congenital ichthyosis, a heterogeneous group of congenital hyperkeratotic genodermatoses with highly variable severity and genetic background. Herein, we report a case of self-improving collodion ichthyosis, a rare subtype of autosomal recessive congenital ichthyosis, characterized by an almost-complete spontaneous resolution of symptoms. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - February 16, 2023 Category: Dermatology Authors: Amoedo, P Source Type: research
Sneddon-Wilkinson disease following COVID-19 vaccination
We describe a previously healthy 21-year-old man who developed acute pustular vesicular eruptions consistent with SPD eight days following the Moderna COVID-19 vaccination. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - February 16, 2023 Category: Dermatology Authors: McCoy, Tatiana Source Type: research
Nirmatrelvir-ritonivir, COVID-19, and possible adverse cutaneous reactions
Nirmatrelvir-ritonivir (Paxlovid) recently received emergency use authorization for the treatment of coronavirus disease 2019 (COVID-19). Literature has linked numerous cutaneous adverse effects to nirmatrelvir and ritonavir, the copackaged tablets within Paxlovid. A review and comparison of these adverse effects to the common cutaneous manifestations of COVID-19 is provided. Numerous drug-to-drug interactions exist between nirmatrelvir-ritonivir and commonly-used medications within dermatology. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - February 16, 2023 Category: Dermatology Authors: Albrecht, J Mark Source Type: research
Reddish-brown, papulonodular skin lesions in the periungual region
We report a 51-year-old woman who presented with ruddy, periungual papules and bilateral joint pain in the hands, consistent with multicentric reticulohistiocytosis. We describe the clinical and histopathologic presentation, therapeutic options, and differential diagnosis of this rare condition. (Source: Dermatology Online Journal)
Source: Dermatology Online Journal - February 16, 2023 Category: Dermatology Authors: Nosewicz, Jacob Source Type: research
