Proteins expressed by viruses transmitted by Aedes aegypti Mosquito
The objective of the present study was to search for the regularities of the proteins expressed by these five viruses, at residues level, and obtain a " bioinformatic fingerprint " to select them. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 19, 2020 Category: Infectious Diseases Source Type: news
Yellow fever – Gabon
On 15 April 2020, WHO received information regarding a confirmed case of yellow fever in Magandi village, Tchibanga city in Nyanga Province of southern Gabon, 590 km from the capital, Libreville. The case is an 83-year-old male with no known vaccination history for yellow fever. He had onset of symptoms on 30 January 2020 and presented to a health facility on 2 February 2020 with abdominal pain and jaundice. Between 2 February and 9 April, he consulted the Urban Health Centre in Tchibanga, the Christian Alliance Hospital in Bongolo and the University hospital in the capital Libreville where the case received anti-malarial...
Source: WHO Disease Outbreaks - June 17, 2020 Category: Infectious Diseases Tags: news Source Type: news
The U.S. Government's Push For Coronavirus Vaccine 'Warp Speed' Faces Potential Black Hole Of Red Tape And Universe Of Unknowns
Dr. Stephen Thomas, who helped develop vaccine candidates for diseases such as Ebola, Zika and MERS, discusses the challenges involved in accelerating development during a pandemic. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 16, 2020 Category: Pharmaceuticals Authors: Stephen Thomas, Contributor Tags: Healthcare /healthcare Innovation /innovation Science /science Business /business Policy /policy Editors' Pick editors-pick Decision Maker decision-maker Coronavirus Source Type: news
MRI tracks brain damage caused by COVID-19
Hospitalized patients with COVID-19 should undergo an MRI exam before being...Read more on AuntMinnie.comRelated Reading: COVID-19 neuro findings marked by mental status, stroke MRI illuminates neurologic manifestations of COVID-19 7T MRI finds promising MS biomarker MRI shows concussion effects last longer than thought Brain abnormalities on CT, MRI indicate severe Zika (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 12, 2020 Category: Radiology Source Type: news
Zika Virus Infection Fast Facts
Read CNN's Fast Facts on Zika and learn more about the virus spread through mosquito bites that can cause birth defects and other neurological defects. (Source: CNN.com - Health)
Source: CNN.com - Health - June 12, 2020 Category: Consumer Health News Source Type: news
Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome
Zika virus (ZIKV) infection during pregnancy can cause a set of severe abnormalities in the fetus known as congenital Zika syndrome (CZS). Experiments with animal models and in vitro systems have substantially contributed to our understanding of the pathophysiology of ZIKV infection. Here, to investigate the molecular basis of CZS in humans, we used a systems biology approach to integrate transcriptomic, proteomic, and genomic data from the postmortem brains of neonates with CZS. We observed that collagens were greatly reduced in expression in CZS brains at both the RNA and protein levels and that neonates with CZS had sev...
Source: Signal Transduction Knowledge Environment - June 8, 2020 Category: Science Authors: Aguiar, R. S., Pohl, F., Morais, G. L., Nogueira, F. C. S., Carvalho, J. B., Guida, L., Arge, L. W. P., Melo, A., Moreira, M. E. L., Cunha, D. P., Gomes, L., Portari, E. A., Velasquez, E., Melani, R. D., Pezzuto, P., de Castro, F. L., Geddes, V. E. V., Ge Tags: STKE Research Resources Source Type: news
Fighting mosquito-borne viruses requires a precise balance of immune cells
(La Jolla Institute for Immunology) In a new study, published June 5, 2020, in the Journal of Experimental Medicine, scientists at La Jolla Institute for Immunology (LJI) shows that antibodies against JEV are 'cross-reactive' and can also recognize Zika virus. Unfortunately, these antibodies can actually make Zika cases more severe. The research, conducted in mice, is the first to show that T cells can counteract this dangerous phenomenon. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 5, 2020 Category: Infectious Diseases Source Type: news
Did Contaminated Water Exacerbate Brazilian Babies' Zika Symptoms?
Elevated levels of a neurotoxin in northeastern Brazil's drinking water and a high incidence of microcephaly in the region led scientists to look for a link, and they found one. (Source: The Scientist)
Source: The Scientist - June 1, 2020 Category: Science Tags: Notebook Magazine Issue Source Type: news
Johnson & Johnson Receives Positive CHMP Opinion for Janssen ’s Investigational Preventive Ebola Vaccine Regimen
Discussions with the FDA are ongoing to define the required data set for filing Janssen’s Ebola vaccine regimen under the FDA’s Animal Rule licensure pathway. About Janssen’s Ebola Vaccine Regimen The Janssen investigational preventive Ebola vaccine regimen (Ad26.ZEBOV, MVA-BN-Filo) utilizes a viral vector strategy in which viruses – in this case adenovirus serotype 26 (Ad26) and Modified Vaccinia Virus Ankara (MVA) – are genetically modified so that they cannot replicate in human cells. In addition, these vectors are modified to safely carry the genetic code of an Ebola virus protein in order to trigger an immun...
Source: Johnson and Johnson - May 29, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news
Politics, Profits Undermine Public Interest in Covid-19 Vaccine Race
By Anis Chowdhury and Jomo Kwame SundaramSYDNEY and KUALA LUMPUR, May 26 2020 (IPS) With well over five million Covid-19 infections worldwide, and deaths exceeding 340,000, the race for an effective vaccine has accelerated since the SARS-Cov-2 virus was first identified as the culprit. Expecting to score politically from being ‘first’ to have a vaccine, US President Trump’s Operation Warp Speed promises to get 300 million doses to Americans by January, after the November polls, following several failed attempts to monopolize vaccines being developed by European companies. Anis Chowdhury More than 115 vaccine develop...
Source: IPS Inter Press Service - Health - May 26, 2020 Category: International Medicine & Public Health Authors: Anis Chowdhury and Jomo Kwame Sundaram Tags: Aid Economy & Trade Featured Global Headlines Health Humanitarian Emergencies TerraViva United Nations Jomo Kwame Sundaram & Anis Chowdhury Source Type: news
Zika infection soon after birth leads to long-term brain and behavior problems
This study, one of the first to shed light on potential long-term effects of Zika infection after birth, shows the infection led to Impairments in memory function, changes in behavior, including reduced social interactions and increased emotional reactions, and some gross motor deficits. These changes corresponded with brain changes on MRI scans, indicating long-term neurologic complications. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 24, 2020 Category: Infectious Diseases Source Type: news
Women's Awareness About Zika Virus During Pregnancy Women's Awareness About Zika Virus During Pregnancy
How aware are women regarding the risk of Zika virus infection during pregnancy, and how often do they discuss these concerns with their healthcare providers?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2020 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
Study indicates the need to revise the protocol for detecting Zika in placenta
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Brazilian researchers show that the virus can infect different placental regions and that collection and storage methods should be taken into consideration to ensure that the results are trustworthy and representative. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 20, 2020 Category: Infectious Diseases Source Type: news
Emerging viral diseases causing serious issues in west Africa
(University of Colorado Anschutz Medical Campus) In a new study, researchers from the Colorado School of Public Health at the University of Colorado Anschutz Medical Campus call attention to the emergence of mosquito-borne viral outbreaks in West Africa, such as dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV) viruses. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 19, 2020 Category: International Medicine & Public Health Source Type: news
Moderna ’s COVID-19 Vaccine Shows Promise, Generating Positive Immune Responses in an Early Study
Earlier today, the biotech company Moderna reported positive results from a phase 1 study of its experimental COVID-19 vaccine, which was was among the first to begin testing in healthy human volunteers in mid-March. The study, led by the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health, involves 45 healthy people who received one of three different doses of the vaccine. According to Moderna, there are encouraging early signs that the shot generates antibodies against the COVID-19 virus, SARS-CoV-2, in levels that were similar to or higher than those seen in the plasma of p...
Source: TIME: Health - May 18, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news